Macrophages as delivery vehicles for anticancer agents

SJ Madsen, H Hirschberg - Therapeutic delivery, 2019 - Taylor & Francis
The delivery of anticancer agents via passive approaches such as the enhanced
permeability and retention effect is unlikely to achieve sufficient concentrations throughout …

The effects of oil-in-water nanoemulsion polyethylene glycol surface density on intracellular stability, pharmacokinetics, and biodistribution in tumor bearing mice

S Hak, Z Garaiova, LT Olsen, AM Nilsen… - Pharmaceutical …, 2015 - Springer
Purpose Lipid-based nanoparticles are extensively studied for drug delivery. These
nanoparticles are often surface-coated with polyethylene glycol (PEG) to improve their …

Design of a Fibroblast Activation Protein–Targeted Radiopharmaceutical Therapy with High Tumor–to–Healthy-Tissue Ratios

R Mukkamala, DJ Carlson, NK Miller… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Because of upregulated expression on cancer-associated fibroblasts, fibroblast activation
protein (FAP) has emerged as an attractive biomarker for the imaging and therapy of solid …

Assessment of the morphological and functional effects of the anti‐angiogenic agent SU11657 on 9L gliosarcoma vasculature using dynamic susceptibility contrast …

CC Quarles, KM Schmainda - Magnetic Resonance in …, 2007 - Wiley Online Library
To investigate the influence of anti‐angiogenic agents on tumor perfusion, we employed a
dynamic susceptibility contrast (DSC)‐MRI method that utilizes a simultaneous gradient …

Predictive value of intratumoral heterogeneity of F-18 FDG uptake for characterization of thyroid nodules according to Bethesda categories of fine needle aspiration …

SJ Kim, S Chang - Endocrine, 2015 - Springer
The current study was aimed to investigate the clinical value of intratumoral heterogeneity of
F-18 FDG uptake for characterization of thyroid nodule (TN) with inconclusive fine-needle …

Molecular characterization of inflammatory genes in sentinel and nonsentinel nodes in melanoma

H Torisu-Itakura, JH Lee, RP Scheri, Y Huynh, X Ye… - Clinical cancer …, 2007 - AACR
Purpose: Identification of regional node metastasis is important for accurate staging and
optimal treatment of early melanoma. We hypothesize that the nodal profile of …

Diffuse optical measurements of head and neck tumor hemodynamics for early prediction of chemoradiation therapy outcomes

L Dong, M Kudrimoti, D Irwin, L Chen… - … of biomedical optics, 2016 - spiedigitallibrary.org
This study used a hybrid near-infrared diffuse optical instrument to monitor tumor
hemodynamic responses to chemoradiation therapy for early prediction of treatment …

VEGFR2-targeted contrast-enhanced ultrasound to distinguish between two anti-angiogenic treatments

T Payen, A Dizeux, C Baldini… - Ultrasound in medicine …, 2015 - Elsevier
The aim of this study was to evaluate the capacity of BR55, an ultrasound contrast agent
specifically targeting vascular endothelial growth factor receptor 2 (VEGFR2), to distinguish …

Dynamic Contrast‐Enhanced Imaging as a Prognostic Tool in Early Diagnosis of Prostate Cancer: Correlation with PSA and Clinical Stage

X Wu, P Reinikainen, M Kapanen… - Contrast Media & …, 2018 - Wiley Online Library
Background and Purpose. Although several methods have been developed to predict the
outcome of patients with prostate cancer, early diagnosis of individual patient remains …

[HTML][HTML] Enhanced detection of desmoplasia by targeted delivery of iron oxide nanoparticles to the tumour-specific extracellular matrix

M Chopra, J Wu, YL Yeow, L Winteringham… - Pharmaceutics, 2021 - mdpi.com
Diagnostic imaging of aggressive cancer with a high stroma content may benefit from the
use of imaging contrast agents targeted with peptides that have high binding affinity to the …