Contrast ultrasonography: necessity of linear data processing for the quantification of tumor vascularization
P Peronneau, N Lassau, I Leguerney… - Ultraschall in der …, 2010 - thieme-connect.com
Ziel: Ziel der Studie war der Vergleich der Wertigkeit nicht komprimierter Ultraschalldaten,
die mittels linearer Powerdetektion von Ultraschallfrequenzen erhoben wurden und im …
die mittels linearer Powerdetektion von Ultraschallfrequenzen erhoben wurden und im …
Cluster analysis of quantitative parametric maps from DCE-MRI: application in evaluating heterogeneity of tumor response to antiangiogenic treatment
Purpose The objective of this study was to compare a clustering approach to conventional
analysis methods for assessing changes in pharmacokinetic parameters obtained from …
analysis methods for assessing changes in pharmacokinetic parameters obtained from …
Quantified pH imaging with hyperpolarized 13C‐bicarbonate
DJ Scholz, MA Janich, U Köllisch… - Magnetic …, 2015 - Wiley Online Library
Purpose Because pH plays a crucial role in several diseases, it is desirable to measure pH
in vivo noninvasively and in a spatially localized manner. Spatial maps of pH were …
in vivo noninvasively and in a spatially localized manner. Spatial maps of pH were …
[HTML][HTML] Design of optimized hypoxia-activated prodrugs using pharmacokinetic/pharmacodynamic modeling
A Foehrenbacher, TW Secomb, WR Wilson… - Frontiers in …, 2013 - frontiersin.org
Hypoxia contributes to resistance of tumors to some cytotoxic drugs and to radiotherapy, but
can in principle be exploited with hypoxia-activated prodrugs (HAP). HAP in clinical …
can in principle be exploited with hypoxia-activated prodrugs (HAP). HAP in clinical …
Functional implications of microvascular heterogeneity for oxygen uptake and utilization
TK Roy, TW Secomb - Physiological Reports, 2022 - Wiley Online Library
In the vascular system, an extensive network structure provides convective and diffusive
transport of oxygen to tissue. In the microcirculation, parameters describing network …
transport of oxygen to tissue. In the microcirculation, parameters describing network …
Comparison of DCE‐MRI kinetic parameters and FMISO‐PET uptake parameters in head and neck cancer patients
U Simoncic, S Leibfarth, S Welz, N Schwenzer… - Medical …, 2017 - Wiley Online Library
Purpose Tumor hypoxia is a major cause of radiation resistance, often present in various
solid tumors. Dynamic [18F]‐fluoromisonidazole (FMISO) PET imaging is able to reliably …
solid tumors. Dynamic [18F]‐fluoromisonidazole (FMISO) PET imaging is able to reliably …
Nasopharyngeal carcinoma: investigation of intratumoral heterogeneity with FDG PET/CT
B Huang, T Chan, DLW Kwong… - American Journal of …, 2012 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to quantitatively evaluate the role of intratumoral
heterogeneity of 18F-FDG uptake in characterizing nasopharyngeal carcinoma (NPC) …
heterogeneity of 18F-FDG uptake in characterizing nasopharyngeal carcinoma (NPC) …
[PDF][PDF] The use of the orthotopic model to validate antivascular therapies for cancer.
M Loi, D Di Paolo, P Becherini, A Zorzoli… - International Journal …, 2011 - researchgate.net
The orthotopic model reproduces aspects of the tumour microenvironment and emulates a
number of important biological features of cancer progression, angiogenesis, metastasis …
number of important biological features of cancer progression, angiogenesis, metastasis …
Estimation of vascular permeability in irregularly shaped cancers using ultrasound poroelastography
MT Islam, E Tasciotti, R Righetti - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
Objective: Vascular permeability (VP) is a mechanical parameter which plays an important
role in cancer initiation, metastasis, and progression. To date, there are only a few non …
role in cancer initiation, metastasis, and progression. To date, there are only a few non …
[HTML][HTML] An image-informed Cahn–Hilliard Keller–Segel multiphase field model for tumor growth with angiogenesis
In this paper we develop a new four-phase tumor growth model with angiogenesis, derived
from a diffuse-interface mixture model composed by a viable tumor component, a necrotic …
from a diffuse-interface mixture model composed by a viable tumor component, a necrotic …