Anemia is a common complication in chronic kidney disease (CKD), and is associated with a
reduced quality of life, and an increased morbidity and mortality. The mechanisms involved …

Chronic kidney disease affects~ 37 million adults in the US, and it is often undiagnosed due
to a lack of apparent symptoms in early stages. Chronic kidney disease (CKD) interferes with …

Background Daprodustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor. In
patients with chronic kidney disease (CKD) who are not undergoing dialysis, the efficacy …

In chronic kidney disease, anemia and disordered iron homeostasis are prevalent and
associated with significant adverse consequences. In 2012, Kidney Disease: Improving …

Although several nanomedicines got clinical approval over the past two decades, the clinical
translation rate is relatively small so far. There are many post-surveillance withdrawals of …

Neutrophil gelatinase-associated lipocalin (NGAL) is a 25-kDa protein that is secreted
mostly by immune cells such as neutrophils, macrophages, and dendritic cells. Its production …

Background: Iron deficiency, with or without anemia, is an adverse prognostic factor in heart
failure (HF). In AFFIRM-AHF (a randomized, double-blind placebo-controlled trial comparing …

The fruits of Ziziphus jujuba, commonly known as jujube, red date or Chinese date, are
taken as fresh or dried food, and as traditional medicine worldwide due to high nutritional …

Though iron is one of the most abundant elements on earth, about a third of the world's
population are affected by iron-deficiency. Main drivers of iron-deficiency are beside the …

The establishment of novel disruptive technologies represents a common requirement for
the sustainable development as reported in the 2030 agenda established by United Nations …