Although usually benign, anterior pituitary tumours occasionally exhibit aggressive
behaviour, with invasion of surrounding tissues, rapid growth, resistance to conventional …

Pituitary adenomas (PAs) are neoplasms derived from the endocrine cells of the anterior
pituitary gland. Most frequently, they are benign tumors, but may sometimes display an …

Objective To describe clinical and pathological characteristics and treatment outcomes in a
large cohort of aggressive pituitary tumours (APT)/pituitary carcinomas (PC). Design …

The tumor microenvironment (TME), the complex environment in which tumors develop, has
been increasingly targeted for cancer treatment in recent years. Aggressive pituitary tumors …

Purpose The purpose of this work was toinvestigate the clinicopathological characteristics at
the initial diagnosis of the pituitary tumor and at pituitary carcinoma (PC) diagnosis …

Most pituitary tumors are considered benign adenomas, and only 0.1%–0.2% of them
present metastasis and are defined as pituitary carcinomas (PCs). Refractory pituitary …

A small subset of pituitary adenomas grows despite maximal treatment with standard
therapies; namely, surgery and radiotherapy. These aggressive tumors demonstrate 2 …

Background The spectrum of neuroendocrine neoplasia (NEN) of the head and neck region
is wide-ranging and diverse, including a variety of diagnoses stretching from benign and low …

This review presents a comprehensive analysis of pituitary adenomas, a type of brain tumor
with diverse behaviors and complexities. We cover various treatment approaches, including …

Pituitary carcinoma (PC) is a rare, aggressive malignancy that comprises 0.1–0.2% of all
pituitary tumors. PC is defined anatomically as a pituitary tumor that metastasizes outside the …