Leveraging multilayered “omics” data for atopic dermatitis: a road map to precision medicine
D Ghosh, JA Bernstein, GK Khurana Hershey… - Frontiers in …, 2018 - frontiersin.org
Atopic dermatitis (AD) is a complex multifactorial inflammatory skin disease that affects~ 280
million people worldwide. About 85% of AD cases begin in childhood, a significant portion of …
million people worldwide. About 85% of AD cases begin in childhood, a significant portion of …
Role of airway epithelial cells in the development of different asthma phenotypes
DP Potaczek, S Miethe, V Schindler, F Alhamdan… - Cellular signalling, 2020 - Elsevier
The term (bronchial) asthma describes a disorder syndrome that comprises several disease
phenotypes, all characterized by chronic inflammation in the bronchial epithelium, with a …
phenotypes, all characterized by chronic inflammation in the bronchial epithelium, with a …
Iron-deficiency in atopic diseases: innate immune priming by allergens and siderophores
F Roth-Walter - Frontiers in Allergy, 2022 - frontiersin.org
Although iron is one of the most abundant elements on earth, about a third of the world's
population are affected by iron deficiency. Main drivers of iron deficiency are beside the …
population are affected by iron deficiency. Main drivers of iron deficiency are beside the …
Initiating pollen sensitization–complex source, complex mechanisms
L Pointner, A Bethanis, M Thaler… - Clinical and translational …, 2020 - Springer
The mechanisms involved in the induction of allergic sensitization by pollen are not fully
understood. Within the last few decades, findings from epidemiological and experimental …
understood. Within the last few decades, findings from epidemiological and experimental …
Short-chain fatty acids augment differentiation and function of human induced regulatory T cells
M Hu, B Alashkar Alhamwe, B Santner-Nanan… - International Journal of …, 2022 - mdpi.com
Regulatory T cells (Tregs) control immune system activity and inhibit inflammation. While, in
mice, short-chain fatty acids (SCFAs) are known to be essential regulators of naturally …
mice, short-chain fatty acids (SCFAs) are known to be essential regulators of naturally …
Nasal DNA methylation at three CpG sites predicts childhood allergic disease
Childhood allergic diseases, including asthma, rhinitis and eczema, are prevalent conditions
that share strong genetic and environmental components. Diagnosis relies on clinical history …
that share strong genetic and environmental components. Diagnosis relies on clinical history …
Extracellular vesicles and asthma—More than just a co-existence
B Alashkar Alhamwe, DP Potaczek, S Miethe… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are membranous structures, which are secreted by almost every
cell type analyzed so far. In addition to their importance for cell-cell communication under …
cell type analyzed so far. In addition to their importance for cell-cell communication under …
The role of epigenetics in allergy and asthma development
BA Alhamwe, F Alhamdan, A Ruhl… - Current opinion in …, 2020 - journals.lww.com
The role of epigenetics in allergy and asthma development : Current Opinion in Allergy and
Clinical Immunology The role of epigenetics in allergy and asthma development : Current …
Clinical Immunology The role of epigenetics in allergy and asthma development : Current …
[HTML][HTML] Indoor microbiome and allergic diseases: from theoretical advances to prevention strategies
X Fu, Z Ou, Y Sun - Eco-Environment & Health, 2022 - Elsevier
The prevalence of allergic diseases, such as asthma, rhinitis, eczema, and sick building
syndrome (SBS), has increased drastically in the past few decades. Current medications can …
syndrome (SBS), has increased drastically in the past few decades. Current medications can …
Epigenetic regulation of airway epithelium immune functions in asthma
B Alashkar Alhamwe, S Miethe… - Frontiers in …, 2020 - frontiersin.org
Asthma is a chronic inflammatory disease of the respiratory tract characterized by recurrent
breathing problems resulting from airway obstruction and hyperresponsiveness. Human …
breathing problems resulting from airway obstruction and hyperresponsiveness. Human …