Food allergy poses a significant clinical and public health burden affecting 2–10% of infants.
Using integrated DNA methylation and transcriptomic profiling, we found that polyclonal …

The respiratory epithelium constitutes the physical barrier between the human body and the
environment, thus providing functional and immunological protection. It is often exposed to …

The past decade has witnessed exponential growth in the generation of high-throughput
human data across almost all known dimensions of biological systems. The discipline of …

Introduction: The development of childhood asthma is caused by a combination of genetic
factors and environmental exposures. Epigenetics describes mechanisms of (heritable) …

Food allergy (FA) prevalence has been increasing over the last few decades and is now a
global health concern. Current diagnostic methods for FA result in a high number of false …

Although M2 macrophages are involved in the orchestration of type 2 inflammation in
allergic diseases, the mechanisms underlying non-coding RNA (ncRNA)-mediated …

The study of epigenetics has improved our understanding of mechanisms underpinning
gene‐environment interactions and is providing new insights in the pathophysiology of …

Asthma is a common complex respiratory disease characterized by chronic airway
inflammation and partially reversible airflow obstruction resulting from genetic and …

Atopic dermatitis (AD) is characterized by severe pruritus and recurrent eczema with a
chronic disease course. Impaired skin barrier function, hyperactivated TH 2 cell–type …

Background The aetiology of inflammatory bowel disease (IBD) is related to genetics and
epigenetics. Epigenetic regulation of the pathogenesis of IBD has not been well defined …