Epigenetic modifications in placenta are associated with the child's sensitization to allergens

H Harb, B Alashkar Alhamwe… - BioMed Research …, 2019 - Wiley Online Library
Prenatal environmental exposures are considered to contribute to the development of
allergic sensitization by epigenetic mechanisms. The role of histone acetylation in the …

Role of CD4+ T Cells in Allergic Airway Diseases: Learning from Murine Models

K Miura, K Inoue, A Ogura, O Kaminuma - International Journal of …, 2020 - mdpi.com
The essential contribution of CD4+ T cells in allergic airway diseases has been
demonstrated, especially by using various murine models of antigen-induced airway …

Differentially methylated DNA regions in early childhood wheezing: An epigenome‐wide study using saliva

M Popovic, V Fiano, F Fasanelli… - Pediatric Allergy and …, 2019 - Wiley Online Library
Background Epigenetics may play a role in wheezing and asthma development. We aimed
to examine infant saliva DNA methylation in association with early childhood wheezing …

Effects of rAmb a 1-loaded PLGA-PEG nanoparticles in a murine model of allergic conjunctivitis

H Cao, L Liu, J Wang, M Gong, R Yuan, J Lu, X Xiao… - Molecules, 2022 - mdpi.com
Ambrosia artemisiifolia (Amb a) contains many allergens. Allergic conjunctivitis caused by
Ambrosia artemisiifolia and its related allergen-specific immunotherapy (AIT) are seldom …

Epigenetic regulation is involved in traffic-related PM2. 5 aggravating allergic airway inflammation in rats

C Wang, J Wang, X Zheng, J Zhang, J Zhang, G Qiao… - Clinical …, 2022 - Elsevier
Increasing fine particulate matter (PM 2.5) and epigenetic modifications are closely
associated with the pathogenesis of asthma, but the definite mechanism remains unclear …

[HTML][HTML] DNA methylation array identifies golli-MBP as a biomarker for disease severity in childhood atopic dermatitis

KD Chen, YH Huang, MMH Guo, LS Chang… - Journal of Investigative …, 2022 - Elsevier
In this study, we investigated the changes in global methylation status and its functional
relevance in childhood atopic dermatitis (AD). Differences in epigenome-scale methylation …

DNA methylation modules in airway smooth muscle are associated with asthma severity

MM Perry, P Lavender, CS Kuo, F Galea… - European …, 2018 - Eur Respiratory Soc
Asthma is a chronic airway inflammatory disorder characterised by airway
hyperresponsiveness, inflammation and remodelling, including airway smooth muscle cell …

Association of STAT6 gene variants with food allergy diagnosed by double‐blind placebo‐controlled food challenges

CD van Ginkel, ME Pettersson, AEJ Dubois… - Allergy, 2018 - Wiley Online Library
This study describes the role of two STAT 6 gene variants in food allergy using data of
patients and their parents who underwent double‐blind placebo‐controlled food challenges …

Epigenetic changes: an emerging potential pharmacological target in allergic rhinitis

J Yang, W Zhong, K Xue, Z Wang - International Immunopharmacology, 2019 - Elsevier
The importance of epigenetics has increased due to identification of its role in the
pathophysiology of a number of diseases including allergic rhinitis. Amongst the different …

Integrated genetic and epigenetic analyses uncover MSI2 association with allergic inflammation

KW Kim, SC Park, HJ Cho, H Jang, J Park… - Journal of Allergy and …, 2021 - Elsevier
Background The relationship between allergic and eosinophilic inflammation, either
systemic or local, in allergic diseases remains unclear. Objective We performed combined …