Progress in the development of TRPV1 small-molecule antagonists: Novel Strategies for pain management

K Zhu, L Wang, TT Liao, W Li, J Zhou, Y You… - European journal of …, 2023 - Elsevier
Transient receptor potential vanilloid 1 (TRPV1) channels are widely distributed in sensory
nerve endings, the central nervous system, and other tissues, functioning as ion channel …

Pentacyclic triterpene-loaded emulsion stabilized by Agaricus blazei Murill polysaccharides: Factorial design and cytoprotection study

M da Silva Campelo, CB Aragão, IMM Teixeira… - International Journal of …, 2023 - Elsevier
In this study, pentacyclic triterpene-loaded emulsions were stabilized by polysaccharides
from Agaricus blazei Murill mushroom (PAb). The drug-excipient compatibility results by …

[PDF][PDF] Anxiolytic-like and anticonvulsant effect in adult zebrafish (Danio rerio) through gabaergic system and molecular docking study of chalcone derived from natural …

J da Cunha Xavier, MKA Ferreira… - Biointerface …, 2021 - biointerfaceresearch.com
Anxiety and seizure are mental disorders commonly treated in the clinic with
benzodiazepines (BZDs). However, long-term treatment with these drugs causes side effects …

Menthol application on healthy and inflamed goat udders changes antimicrobial components in milk

R Ohno, N Suzuki, Y Tsugami, T Nii… - Animal Science …, 2023 - Wiley Online Library
Mammary glands with mastitis are usually treated with antibiotics in combination with anti‐
inflammatory drug application on the udder skin. Menthol is an anti‐inflammatory drug. The …

Heterocyclic chalcone (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(thiophen-2-yl) prop-2-en-1-one derived from a natural product with antinociceptive, anti …

MKA Ferreira, WPO Freitas, IM Barbosa, MN da Rocha… - 3 Biotech, 2023 - Springer
Diabetes is a disease linked to pathologies, such as chronic inflammation, neuropathy, and
pain. The synthesis by the Claisen− Schmidt condensation reaction aims to obtain medium …

A review on the secretory structures, bioactive compounds and biological activities of selected Combretum species

S Bantho, Y Naidoo, YH Dewir, M Singh - South African Journal of Botany, 2023 - Elsevier
Species of Combretum are highly valued in Africa due to the plethora of traditional medicinal
uses they may offer. Species such as Combretum molle, Combretum erythrophyllum …

Antinociceptive, anti-inflammatory and hypoglycemic activities of the ethanolic Turnera subulata Sm. flower extract in adult zebrafish (Danio rerio)

EL Rebouças, AW da Silva, MC Rodrigues… - Journal of …, 2022 - Taylor & Francis
Turnera subulata Sm. belongs to the family Turneraceae and is found in Brazil. The present
study evaluated the antinociceptive, anti-inflammatory, and hypoglycemic potential of T …

Antiproliferative activity on Trypanosoma cruzi (Y strain) of the triterpene 3β,6β,16β-trihidroxilup-20 (29)-ene isolated from Combretum leprosum

JIF de Araújo, NL Aires… - Journal of …, 2022 - Taylor & Francis
Chagas disease infects approximately seven million people worldwide. Benznidazole is
effective only in the acute phase of the disease, with an average cure rate of 80% between …

[HTML][HTML] Isolation, purification, and characterization of lectins from medicinal plant Combretum glutinosum seeds endowed with analgesic and antiulcer properties

EH Naser, AH Idries, SAA Elmubarak, MB Dafalla… - Biochimie, 2024 - Elsevier
In the pursuit of safer and more effective treatments, there is a growing interest in plant-
derived compounds, particularly lectins, because of their diverse pharmacological …

Biological Activity of Combretum erythrophyllum: Antioxidant, Apoptotic, and Cytotoxic Activity of the Leaf and Stembark Extract

S Bantho, Y Naidoo, YH Dewir, M Singh, A Bantho - Horticulturae, 2023 - mdpi.com
Species of Combretum are highly valued in Africa due to the plethora of traditional medicinal
uses they may offer and the medicinally important phytometabolites they are known to …