During the perinatal period, the brain is particularly sensitive to remodelling by
environmental factors. Adverse early‐life experiences, such as stress exposure or …

Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

Childhood maltreatment is likely to influence fundamental biological processes and engrave
long-lasting epigenetic marks, leading to adverse health outcomes in adulthood. We aimed …

This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

Experimental animal models have demonstrated that one of the primary consequences of
prenatal stress is increased fear and anxiety in the offspring. Few prospective human studies …

Methyl donors such as choline, betaine, folic acid, methionine, and vitamins B6 and B12 are
critical players in the one-carbon metabolism and have neuroprotective functions. The one …

Objective Gene expression changes have been reported in the brains of suicide completers.
More recently, differences in promoter DNA methylation between suicide completers and …

Neurological and neuropsychiatric disorders affect men and women differently. Multiple
sclerosis, Alzheimer's disease, anxiety disorders, depression, meningiomas and late-onset …

Home visiting is an important mechanism for minimizing the lifelong effects of early
childhood adversity. To do so, it must be informed by the biology of early brain and child …

BackgroundTo develop latent classes of exposure to traumatic experiences before the age
of 13 years in an urban community sample and to use these latent classes to predict the …