Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …

Introduction: Pseudomonas aeruginosa infections are prevalent amongst chronic
rhinosinusitis (CRS) sufferers. Many P. aeruginosa strains form biofilms, leading to treatment …

Background Invasive methods requiring general anaesthesia are needed to sample the lung
microbiota in young children who do not expectorate. This poses substantial challenges to …

Microbial population polymorphisms are commonly observed in natural environments,
including long-term infected hosts. However, the underlying processes promoting and …

Bacteria in natural, industrial and clinical settings predominantly live in biofilms, ie, sessile
structured microbial communities encased in self‐produced extracellular matrix material …

Chronic Pseudomonas aeruginosa biofilm lung infection in cystic fibrosis patients is the best
described biofilm infection in medicine. The initial focus can be the paranasal sinuses and …

Pseudomonas aeruginosa notoriously adapts to the airways of people with cystic fibrosis
(CF), yet how infection-site biogeography and associated evolutionary processes vary as …

A continuously mixed series of microbial communities inhabits various points of the
respiratory tract, with community composition determined by distance from colonization …

Chronic bacterial infections are a key feature of a variety of lung conditions. The
opportunistic bacterium, Pseudomonas aeruginosa, is extremely skilled at both colonizing …