[PDF][PDF] Statistical methods for analysis of time course gene expression data

H Li, Y Luan, F Hong, Y Li - Frontiers in Bioscience, 2002 - article.imrpress.com
Introduction 3. Materials and Methods 3.1. Time lagged correlation coefficient analysis 3.2.
The mixed-effects model for time-course gene expression data 3.3. Methods for clustering …

[HTML][HTML] TRRD: database on transcription regulatory regions of eukaryotic genes

AE Kel', NA Kolchanov, OV Kel'… - Molecular …, 1997 - wwwmgs.bionet.nsc.ru
format of the TRRD complies with the model of hierarchical organization of transcription
regulatory regions of eukaryotic genes. The current version of TRRD covers more than 300 …

Composition-sensitive analysis of the human genome for regulatory signals

OV Kel-Margoulis, D Tchekmenev, AE Kel… - In Silico …, 2003 - content.iospress.com
Known transcription regulatory signals which generally act as transcription factor binding
sites (TFs) differ significantly in their base composition. Therefore, their occurrence in a …

Finding genes by computer: probabilistic and discriminative approaches

T Jiang, Y Xu, MQ Zhang - 2002 - ieeexplore.ieee.org
This chapter contains sections titled: General Features of Eukaryotic Genes, Functional
Signals Description and Identification, ORF, Exon, and Single Gene Prediction Approaches …

HOX Pro: a specialized database for clusters and networks of homeobox genes

AV Spirov, T Bowler, J Reinitz - Nucleic Acids Research, 2000 - academic.oup.com
It is now clear that the homeobox motif is well conserved across metazoan phyla. It has been
established experimentally that a subset of genes containing this motif plays key roles in the …

Experimental data of a single promoter can be used for in silico detection of genes with related regulation in the absence of sequence similarity

V Gailus-Durner, M Scherf, T Werner - Mammalian Genome, 2001 - Springer
Gene expression is presently a major focus in genome analysis, and the experimental data
on regulatory mechanisms and functional transcription factor binding sites are steadily …

Binding of YY1 to a site overlapping a weak TATA box is essential for transcription from the uteroglobin promoter in endometrial cells

J Klug, M Beato - Molecular and cellular biology, 1996 - Taylor & Francis
The gene for rabbit uteroglobin codes for a small calcium-, steroid-, and biphenyl metabolite-
binding homodimeric protein which is expressed in a variety of epithelial cell types such as …

Changes in primary DNA sequence complexity influence the phenotypic consequences of mutations in human gene regulatory regions

M Krawczak, N Chuzhanova, P Stenson, B Johansen… - Human genetics, 2000 - Springer
No general rules have been proposed to account for the functional consequences of gene
regulatory mutations. In a first attempt to establish the nature of such rules, an analysis was …

ExpertDiscovery and UGENE integrated system for intelligent analysis of regulatory regions of genes

YY Vaskin, IV Khomicheva, EV Ignatieva… - In Silico …, 2012 - content.iospress.com
The task of automatic extraction of the hierarchical structure of eukaryotic gene regulatory
regions is in the junction of the fields of biology, mathematics and information technologies …

Finding and decrypting of promoters contributes to the elucidation of gene function

T Werner - In Silico Biology, 2002 - content.iospress.com
The combination of full-scale genomic sequencing with high throughput expression analysis
provides a new and largely unexploited basis for in silico functional genomics. Recent break …