Combinatorial regulation is a powerful mechanism for generating specificity in gene
expression, and it is thought to play a pivotal role in the formation of the complex gene …

GeneExpress system has been designed to integrate description, analysis, and recognition
of eukaryotic regulatory sequences. The system includes 5 basic units:(1) GeneNet contains …

The last 15 years in development of biology were marked with accumulation of
unprecedentedly huge arrays of experimental data. The information was amassed with …

The effort to sequence the human genome is now moving toward a c-clusion. As all of the
protein coding sequences are described, an increasing emphasis will be placed on …

Database‐assisted bioinformatic approaches facilitate the analysis of gene regulatory
sequences and allow the identification of putative transcription factor binding sites or …

Background We previously demonstrated that gene expression profiles during neuronal
differentiation in vitro and hippocampal development in vivo were very similar, due to a …

Solid tumors are a leading cause of mortality in adults across the world. Treatment options
are often limited trough toxicity in non-target tissues. Mesenchymal stem cells (MSCs) …

Задача автоматического восстановления иерархической структуры регуляторной
области эукариотического гена поставлена на стыке биологии, математики и …

Regulatory regions share several common features despite their obvious divergence in
sequence. Most of these common features are not evident directly from the nucleotide …