Lung cancer in patients who have never smoked—An emerging disease

J LoPiccolo, A Gusev, DC Christiani… - Nature Reviews Clinical …, 2024 - nature.com
Lung cancer is the most common cause of cancer-related deaths globally. Although smoking-
related lung cancers continue to account for the majority of diagnoses, smoking rates have …

[HTML][HTML] COPD and the gut-lung axis: the therapeutic potential of fibre

A Vaughan, ZA Frazer, PM Hansbro… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Current management strategies for chronic obstructive pulmonary disease (COPD)
incorporate a step-wise, multidisciplinary approach to effectively manage patient symptoms …

[HTML][HTML] The effects of epithelial–mesenchymal transitions in COPD induced by cigarette smoke: an update

X Su, W Wu, Z Zhu, X Lin, Y Zeng - Respiratory research, 2022 - Springer
Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …

Incorporating coexisting chronic illness into decisions about patient selection for lung cancer screening. An official American Thoracic Society research statement

MP Rivera, NT Tanner, GA Silvestri… - American journal of …, 2018 - atsjournals.org
Background: Lung cancer screening (LCS) has the potential to reduce the risk of lung
cancer death in healthy individuals, but the impact of coexisting chronic illnesses on LCS …

[HTML][HTML] Chronic obstructive pulmonary disease (COPD) and lung cancer screening

RP Young, RJ Hopkins - Translational lung cancer research, 2018 - ncbi.nlm.nih.gov
The primary aim of lung cancer screening is to improve survival from lung cancer by
identifying early stage non-small cell lung cancers and prolong survival through their …

[HTML][HTML] Lung function impairment in the German Lung Cancer Screening Intervention Study (LUSI): prevalence, symptoms, and associations with lung cancer risk …

R Kaaks, E Christodoulou, E Motsch… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background Lung cancer screening may provide a favorable opportunity for a spirometry
examination, to diagnose participants with undiagnosed lung function impairments, or to …

Low-dose CT screening for lung cancer: evidence from 2 decades of study

DS Gierada, WC Black, C Chiles, PF Pinsky… - Radiology: Imaging …, 2020 - pubs.rsna.org
Lung cancer remains the overwhelmingly greatest cause of cancer death in the United
States, accounting for more annual deaths than breast, prostate, and colon cancer …

Airflow limitation and mortality during cancer screening in the National Lung Screening Trial: why quantifying airflow limitation matters

RP Young, RC Ward, RJ Scott, GD Gamble, G Silvestri - thorax, 2023 - thorax.bmj.com
Importance Current eligibility criteria for lung cancer (LC) screening are derived from
randomised controlled trials and primarily based on age and smoking history. However, the …

Incidental findings on lung cancer screening: significance and management

EB Tsai, C Chiles, BW Carter, MCB Godoy… - Seminars in Ultrasound …, 2018 - Elsevier
Incidental findings are commonly detected by computed tomography, but distinguishing
which findings have little or no clinical consequence and which are significant enough to …

[HTML][HTML] Lung cancer screening CT-based coronary artery calcification in predicting cardiovascular events: a systematic review and meta-analysis

L Fan, K Fan - Medicine, 2018 - journals.lww.com
Background: Coronary artery calcificition (CAC) is a well-established predictor of
cardiovascular events (CVEs). We aimed to evaluate whether lung cancer screening …