Diabetic kidney disease (DKD) is a chronic complication of diabetes and the leading cause
of end-stage renal disease (ESRD) worldwide. Currently, there are limited therapeutic drugs …

Autophagy is a protective mechanism through which cells degrade and recycle proteins and
organelles to maintain cellular homeostasis and integrity. An accumulating body of evidence …

Diabetic nephropathy (DN) is a worldwide health problem with increasing incidence.
Diosgenin (DIO) is a natural active ingredient extracted from Chinese yams (Rhizoma …

The incidence of diabetes mellitus (DM) is gradually increasing, making it a widespread
global health concern. Cadmium (Cd) is a common toxic heavy metal in the environment …

Melatonin (MLT) is a biologically active indoleamine involved in regulating various
biological rhythms, which is deficient in individuals with Type 2 diabetes. The present study …

Hyperglycemia, characterized by high blood glucose levels resulting from pancreatic beta
cell dysfunction or impaired insulin signaling, is a contributing factor in the development of …

Background: Diabetic nephropathy (DN) is the most common complication of diabetes, and
its pathogenesis is complex involving a variety of programmed cell death, inflammatory …

Tiliroside, a natural flavonoid, has various biological activities and improves several
inflammatory diseases in rodents. However, the effect of Tiliroside on lipopolysaccharide …

Diabetic nephropathy (DN) is a common complication of diabetes, characterized by renal
fibrosis and poor patient prognosis. Hederagenin (HDG) has shown promising improvement …

This study was designed to probe the effect of chaperone-assisted selective autophagy
(CASA) on the maintenance of proteostasis during exhaustive exercise and uncover the …