α2-agonists have been extensively used and studied in anaesthesia and intensive care
medicine. A list of benefits includes anxiolysis, blood pressure stabilization, analgesia …

The need for blood pressure control before elective surgery depends on the degree and
type of hypertension and the presence of other cardiovascular risk factors. Although blood …

The purpose of this study was to evaluate oral clonidine in a dose of 0.3 mg as a routine
premedicant. Sixty-nine normotensive female patients were studied in a randomized double …

Many principles that originate in the operating room and in fluid mechanics modeling are
relevant to endotracheal intubation in the pulmonary and critical care setting. These factors …

Results: Analysis revealed that the heart rate, systolic, diastolic and mean arterial blood
pressure significantly differed between groups (p< 0.001, p= 0.003, p< 0.001, p< 0.001 …

Abstract Study Objective: To determine the effects of oral clonidine premeditation sedative,
anxiolytic, and hemodynamic responses during the immediate preoperative period …

Aims: The aim was to compare the effect of intravenous (IV) infusion of dexmedetomidine
and clonidine on the pressor response among patients undergoing tracheal intubation in …

Clonidine is classified as an imidazoline and it is the prototypical alpha-2 receptor agonists.
It has been used for several years to treat hypertension. It has also been used,“off label”, for …

Background: Laryngoscopy and tracheal intubation are noxious stimuli which evoke a
transient but marked sympathetic response. Alpha-2 adrenoceptor agonists attenuate the …

The effect of clonidine on the pressor and heart rate response to tracheal intubation was
studied in a placebo‐controlled, randomised, double‐blind trial. Thirty patients were …