1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships
Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …
resistance associated with the currently used anticancer agents create an urgent need to …
Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids
Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …
aroused great interest in medicinal chemists for the development of new drugs or drug …
Nitrogen containing heterocycles as anticancer agents: a medicinal chemistry perspective
Cancer is one of the major healthcare challenges across the globe. Several anticancer
drugs are available on the market but they either lack specificity or have poor safety, severe …
drugs are available on the market but they either lack specificity or have poor safety, severe …
A review on synthesis, mechanism of action, and structure-activity relationships of 1, 2, 3-triazole-based α-glucosidase inhibitors as promising anti-diabetic agents
Abstract α-Glucosidase is a key enzyme in hydrolysis of carbohydrates to glucose and
located in the small intestine brush border. Inhibition of this enzyme delay the release of …
located in the small intestine brush border. Inhibition of this enzyme delay the release of …
Recent advances on quinazoline derivatives: A potential bioactive scaffold in medicinal chemistry
This paper intended to explore and discover recent therapeutic agents in the area of
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …
Design, synthesis, computational study and cytotoxic evaluation of some new quinazoline derivatives containing pyrimidine moiety
Quinazoline derivatives, as an important category of heterocyclic compounds, have received
much attention for the design and development of new drugs due to their various …
much attention for the design and development of new drugs due to their various …
Medicinal chemistry of quinazolines as anticancer agents targeting tyrosine kinases
MF Zayed - Scientia Pharmaceutica, 2023 - mdpi.com
Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …
[HTML][HTML] Chemical insights into the synthetic chemistry of quinazolines: Recent advances
In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines,
possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV …
possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV …
Nanocatalyzed synthetic approach for quinazoline and quinazolinone derivatives: A review (2015–present)
Quinazolines and their derivative are among the most significant heterocyclic compounds
due to their several chemical reactivities and vital range of biological activity. Although a …
due to their several chemical reactivities and vital range of biological activity. Although a …
Medicinal chemistry of quinazolines as analgesic and anti-inflammatory agents
MF Zayed - ChemEngineering, 2022 - mdpi.com
Quinazoline is an essential scaffold, known to be linked with various biological activities.
Some of the prominent biological activities of this system are analgesic, anti-inflammatory …
Some of the prominent biological activities of this system are analgesic, anti-inflammatory …