Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics
Decades of neurobiological research have disclosed the diverse manners in which the
response properties of neurons are dynamically modulated to support adaptive cognitive …
response properties of neurons are dynamically modulated to support adaptive cognitive …
Revisiting the role of neurotransmitters in epilepsy: An updated review
Epilepsy is a neurologicaldisorder characterized by persistent predisposition to recurrent
seizurescaused by abnormal neuronal activity in the brain. Epileptic seizures maydevelop …
seizurescaused by abnormal neuronal activity in the brain. Epileptic seizures maydevelop …
Fast-specific fluorescent probes to visualize norepinephrine signaling pathways and its flux in the epileptic mice brain
H Yan, Y Wang, F Huo, C Yin - Journal of the American Chemical …, 2023 - ACS Publications
Norepinephrine (NE) is synthesized in the locus coeruleus and widely projected throughout
the brain and spinal cord. It regulates various actions and consciousness linked to a variety …
the brain and spinal cord. It regulates various actions and consciousness linked to a variety …
[HTML][HTML] Uncertainty and stress: Why it causes diseases and how it is mastered by the brain
A Peters, BS McEwen, K Friston - Progress in neurobiology, 2017 - Elsevier
The term 'stress'–coined in 1936–has many definitions, but until now has lacked a
theoretical foundation. Here we present an information-theoretic approach–based on the …
theoretical foundation. Here we present an information-theoretic approach–based on the …
Using neuroscience to help understand fear and anxiety: a two-system framework
Tremendous progress has been made in basic neuroscience in recent decades. One area
that has been especially successful is research on how the brain detects and responds to …
that has been especially successful is research on how the brain detects and responds to …
[HTML][HTML] Beyond eye gaze: What else can eyetracking reveal about cognition and cognitive development?
MK Eckstein, B Guerra-Carrillo, ATM Singley… - Developmental cognitive …, 2017 - Elsevier
This review provides an introduction to two eyetracking measures that can be used to study
cognitive development and plasticity: pupil dilation and spontaneous blink rate. We begin by …
cognitive development and plasticity: pupil dilation and spontaneous blink rate. We begin by …
School readiness and self-regulation: A developmental psychobiological approach
Research on the development of self-regulation in young children provides a unifying
framework for the study of school readiness. Self-regulation abilities allow for engagement in …
framework for the study of school readiness. Self-regulation abilities allow for engagement in …
Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory
Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …
processing of other information. Here, we propose that, under arousal, local glutamate levels …
[HTML][HTML] Rapid reconfiguration of the functional connectome after chemogenetic locus coeruleus activation
The locus coeruleus (LC) supplies norepinephrine (NE) to the entire forebrain and regulates
many fundamental brain functions. Studies in humans have suggested that strong LC …
many fundamental brain functions. Studies in humans have suggested that strong LC …
The locus coeruleus: essential for maintaining cognitive function and the aging brain
Research on cognitive aging has focused on how decline in various cortical and
hippocampal regions influence cognition. However, brainstem regions play essential …
hippocampal regions influence cognition. However, brainstem regions play essential …