Enzymes can be engineered at the level of their amino acid sequences to optimize key
properties such as expression, stability, substrate range, and catalytic efficiency─ or even to …

Achieving cost-competitive bio-based processes requires development of stable and
selective biocatalysts. Their realization through in vitro enzyme characterization and …

Protein engineering is essential for altering the substrate scope, catalytic activity and
selectivity of enzymes for applications in biocatalysis. However, traditional approaches, such …

Stereodivergent engineering of one enzyme to create stereocomplementary variants for
synthesizing optically pure molecules with tailor‐made (R) or (S) configurations on an …

Conspectus Enzymes are desired catalysts for chemical synthesis, because they can be
engineered to provide unparalleled levels of efficiency and selectivity. Yet, despite the …

Cytochrome P450 BM3 monooxygenase is the topic of extensive research as many
researchers have evolved this enzyme to generate a variety of products. However, the …

Single‐atom nanozymes (SAzymes) showcase not only uniformly dispersed active sites but
also meticulously engineered coordination structures. These intricate architectures bestow …

Repurposing enzymes to catalyze non‐natural asymmetric transformations that are difficult
to achieve using traditional chemical methods is of significant importance. Although radical …

Biocatalysis holds immense potential for pharmaceutical development as it enables
synthetic routes to various chiral building blocks with unparalleled selectivity. Therein …

Biocatalysis is entering a promising era as a data-driven science. High-throughput
experimentation generates a rapidly increasing stream of biocatalytic data, which is the raw …