Vascular endothelial cells and innate immunity
In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …
participate in both innate and adaptive immune responses. We previously reported that, in …
Beneficial effects of citrus flavonoids on cardiovascular and metabolic health
AM Mahmoud, RJ Hernandez Bautista… - Oxidative medicine …, 2019 - Wiley Online Library
The prevalence of cardiovascular disease (CVD) is increasing over time. CVD is a
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …
HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry
C Wei, L Wan, Q Yan, X Wang, J Zhang, X Yang… - Nature …, 2020 - nature.com
Responsible for the ongoing coronavirus disease 19 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through binding of the …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through binding of the …
Hypertriglyceridemia and atherosclerosis
J Peng, F Luo, G Ruan, R Peng, X Li - Lipids in health and disease, 2017 - Springer
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has
been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an …
been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an …
Targeting inflammation in metabolic syndrome
FK Welty, A Alfaddagh, TK Elajami - Translational research, 2016 - Elsevier
The metabolic syndrome (MetS) is comprised of a cluster of closely related risk factors,
including visceral adiposity, insulin resistance, hypertension, high triglyceride, and low high …
including visceral adiposity, insulin resistance, hypertension, high triglyceride, and low high …
An abundant dysfunctional apolipoprotein A1 in human atheroma
Y Huang, JA DiDonato, BS Levison, D Schmitt, L Li… - Nature medicine, 2014 - nature.com
Recent studies have indicated that high-density lipoproteins (HDLs) and their major
structural protein, apolipoprotein A1 (apoA1), recovered from human atheroma are …
structural protein, apolipoprotein A1 (apoA1), recovered from human atheroma are …
High-density lipoprotein: vascular protective effects, dysfunction, and potential as therapeutic target
TF Lüscher, U Landmesser, A von Eckardstein… - Circulation …, 2014 - Am Heart Assoc
High-density lipoprotein (HDL) is a complex mixture of lipoproteins that is associated with
many minor proteins and lipids that influence the function of HDL. Although HDL is a …
many minor proteins and lipids that influence the function of HDL. Although HDL is a …
Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
DE Gaddis, LE Padgett, R Wu, C McSkimming… - Nature …, 2018 - nature.com
Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis.
Here we show that during atherogenesis Treg cells lose Foxp3 expression and their …
Here we show that during atherogenesis Treg cells lose Foxp3 expression and their …
The ins and outs of lipid rafts: Functions in intracellular cholesterol homeostasis, microparticles, and cell membranes: Thematic Review Series: Biology of Lipid Rafts
AB Ouweneel, MJ Thomas, MG Sorci-Thomas - Journal of lipid research, 2020 - ASBMB
Cellular membranes are not homogenous mixtures of proteins; rather, they are segregated
into microdomains on the basis of preferential association between specific lipids and …
into microdomains on the basis of preferential association between specific lipids and …
How do elevated triglycerides and low HDL-cholesterol affect inflammation and atherothrombosis?
FK Welty - Current cardiology reports, 2013 - Springer
This review article summarizes recent research into the mechanisms as to how elevated
levels of triglyceride (TG) and low levels of high-density-lipoprotein cholesterol (HDL-C) …
levels of triglyceride (TG) and low levels of high-density-lipoprotein cholesterol (HDL-C) …