The promising therapeutic approaches for radiation-induced pulmonary fibrosis: targeting radiation-induced mesenchymal transition of alveolar type II epithelial cells
P Wang, Z Yan, PK Zhou, Y Gu - International Journal of Molecular …, 2022 - mdpi.com
Radiation-induced pulmonary fibrosis (RIPF) is a common consequence of radiation for
thoracic tumors, and is accompanied by gradual and irreversible organ failure. This severely …
thoracic tumors, and is accompanied by gradual and irreversible organ failure. This severely …
[HTML][HTML] The scheme, and regulative mechanism of pyroptosis, ferroptosis, and necroptosis in radiation injury
J Ning, L Chen, Y Zeng, G Xiao, W Tian… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Radiotherapy (RT) stands as the primary treatment for tumors, but it inevitably causes
damage to normal cells. Consequently, radiation injury is a crucial consideration for …
damage to normal cells. Consequently, radiation injury is a crucial consideration for …
Activation of Nrf2/ARE pathway by Anisodamine (654-2) for Inhibition of cellular aging and alleviation of Radiation-Induced lung injury
H Guo, J Chen, H Yu, L Dong, R Yu, Q Li, J Song… - International …, 2023 - Elsevier
Background Radiation-induced lung injury (RILI) is a common side effect of thoracic tumor
radiotherapy, including early-stage radiation-induced lung injury (RP) and late-stage …
radiotherapy, including early-stage radiation-induced lung injury (RP) and late-stage …
[HTML][HTML] Lonicera japonica polysaccharides improve longevity and fitness of Caenorhabditis elegans by activating DAF-16
J Zhu, Y Jia, C Wang, W Zhou, Y Shu, K Zhang… - International Journal of …, 2023 - Elsevier
Polysaccharide is one of the main active ingredients in Lonicera japonica Thunb.(L.
japonica). In this study, we examined the anti-aging activities of L. japonica polysaccharides …
japonica). In this study, we examined the anti-aging activities of L. japonica polysaccharides …
Sennoside A is a novel inhibitor targeting caspase-1
J Wu, Y Lan, X Shi, W Huang, S Li, J Zhang, H Wang… - Food & Function, 2022 - pubs.rsc.org
The assembly of inflammasomes drives caspase-1 activation, which further promotes
proinflammatory cytokine secretion and downstream pyroptosis. The discovery of novel …
proinflammatory cytokine secretion and downstream pyroptosis. The discovery of novel …
Monophosphoryl lipid A ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the M1 phenotype
X Guo, L Du, N Ma, P Zhang, Y Wang, Y Han… - Journal of Translational …, 2022 - Springer
Background Radiation-induced lung injury (RILI) often occurs during clinical chest
radiotherapy and acute irradiation from accidental nuclear leakage. This study explored the …
radiotherapy and acute irradiation from accidental nuclear leakage. This study explored the …
Inhibition of MyD88 attenuates angiotensin II-induced hypertensive kidney disease via regulating renal inflammation
K Lin, W Luo, N Yang, L Su, H Zhou, X Hu… - International …, 2022 - Elsevier
Background Kidney damage is a frequent event in the course of hypertension. Recent
researches highlighted a critical role of non-hemodynamic activities of angiotensin II (Ang II) …
researches highlighted a critical role of non-hemodynamic activities of angiotensin II (Ang II) …
Regulatory Cues in Pulmonary Fibrosis—With Emphasis on the AIM2 Inflammasome
YH Tseng, IC Chen, WC Li, JH Hsu - International Journal of Molecular …, 2023 - mdpi.com
Pulmonary fibrosis (PF) is a chronic lung disorder characterized by the presence of scarred
and thickened lung tissues. Although the Food and Drug Administration approved two …
and thickened lung tissues. Although the Food and Drug Administration approved two …
Pyroptotic cell death: an emerging therapeutic opportunity for radiotherapy
H Li, T Yang, J Zhang, K Xue, X Ma, B Yu, X Jin - Cell Death Discovery, 2024 - nature.com
Pyroptotic cell death, an inflammatory form of programmed cell death (PCD), is emerging as
a potential therapeutic opportunity for radiotherapy (RT). RT is commonly used for cancer …
a potential therapeutic opportunity for radiotherapy (RT). RT is commonly used for cancer …
[HTML][HTML] The pulmonary biopharmaceutics and anti-inflammatory effects after intratracheal and intravenous administration of Re-Du-Ning injection
W Jia-Xing, L Chao-Yi, C Wei-Ya, C Yi-Jun… - Biomedicine & …, 2023 - Elsevier
Abstract Background Re-Du-Ning injection (RDN) is a renowned heat-clearing traditional
Chinese medicine for the treatment of respiratory diseases owing to its anti-inflammatory …
Chinese medicine for the treatment of respiratory diseases owing to its anti-inflammatory …