Unravelling the potential of mitochondria-targeted liposomes for enhanced cancer treatment

MS Khan, BHJ Gowda, WH Almalki, T Singh… - Drug Discovery …, 2023 - Elsevier
Highlights•Mitochondria are involved in various physiochemical and biochemical
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …

The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics

BHJ Gowda, MG Ahmed, SA Alshehri, S Wahab… - Environmental …, 2023 - Elsevier
Lyotropic liquid crystals are self-assembled, non-lamellar, and mesophase nanostructured
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …

PRMT6 methylation of STAT3 regulates tumor metastasis in breast cancer

Q Chen, Q Hu, Y Chen, N Shen, N Zhang, A Li… - Cell death & …, 2023 - nature.com
Overcoming distant metastasis stands as a paramount challenge in enhancing the outcomes
of breast cancer treatments. Thus, delving deeper into comprehending the intricate …

An enzyme-powered microRNA discriminator for the subtype-specific diagnosis of breast cancer

H Mao, Y Cao, Z Zou, J Xia, J Zhao - Chemical Science, 2023 - pubs.rsc.org
Breast cancer, a disease with highly heterogeneous features, is the most common
malignancy diagnosed in people worldwide. Early diagnosis of breast cancer is crucial for …

A Mitochondria‐Targeted Ferroptosis Inducer Activated by Glutathione‐Responsive Imaging and Depletion for Triple Negative Breast Cancer Theranostics

H Gan, X Huang, X Luo, J Li, B Mo… - Advanced …, 2023 - Wiley Online Library
Ferroptosis is a new type of iron‐dependent programmed cell death characterized by
glutathione (GSH) depletion, selenoprotein glutathione peroxidase 4 (GPX4) inactivation …

Nano-modulators with the function of disrupting mitochondrial Ca2+ homeostasis and photothermal conversion for synergistic breast cancer therapy

C Wang, T Li, Z Wang, Y Li, Y Liu, M Xu… - Journal of …, 2023 - Springer
Breast cancer treatment has been a global puzzle, and apoptosis strategies based on
mitochondrial Ca2+ overload have attracted extensive attention. However, various …

Oxidation-derived anticancer potential of sumanene–ferrocene conjugates

A Kasprzak, A Zuchowska, P Romanczuk… - Dalton …, 2024 - pubs.rsc.org
An effective synthetic protocol towards the oxidation of sumanene–ferrocene conjugates
bearing one to four ferrocene moieties has been established. The oxidation protocol was …

[HTML][HTML] CD63+ cancer-associated fibroblasts confer CDK4/6 inhibitor resistance to breast cancer cells by exosomal miR-20

J Sun, R Du, X Li, C Liu, D Wang, X He, G Li, K Zhang… - Cancer Letters, 2024 - Elsevier
Abstract Cyclin-dependent kinase 4 (CDK4) and CDK6 inhibitors (CDK4/6i) have rapidly
received Food and Drug Administration (FDA) approval as a new type of therapy for patients …

Anti-Xanthine Oxidase 5′-Hydroxyhericenes A–D from the Edible Mushroom Hericium erinaceus and Structure Revision of 3-[2,3-Dihydroxy-4-(hydroxymethyl) …

T Thongkongkaew, N Jariyasopit, S Khoomrung… - ACS …, 2023 - ACS Publications
Hericium erinaceus is an edible mushroom with diverse pharmaceutical applications.
Although this mushroom is an attractive source of natural products for cancer treatment, little …

[HTML][HTML] Effects of organized screening programs on breast cancer screening, incidence, and mortality in Europe

S Guthmuller, V Carrieri, A Wübker - Journal of Health Economics, 2023 - Elsevier
We link data on regional Organized Screening Programs (OSPs) throughout Europe with
survey data and population-based cancer registries to estimate effects of OSPs on breast …