The role of hyperpolarized 129xenon in MR imaging of pulmonary function

L Ebner, J Kammerman, B Driehuys… - European journal of …, 2017 - Elsevier
In the last two decades, functional imaging of the lungs using hyperpolarized noble gases
has entered the clinical stage. Both helium (3 He) and xenon (129 Xe) gas have been …

Lung imaging in asthmatic patients: the picture is clearer

M Castro, SB Fain, EA Hoffman, DS Gierada… - Journal of Allergy and …, 2011 - Elsevier
Imaging of the lungs in patients with asthma has evolved dramatically over the last decade
with sophisticated techniques, such as computed tomography, magnetic resonance imaging …

Radiologic imaging in cystic fibrosis: cumulative effective dose and changing trends over 2 decades

OJ O'Connell, S McWilliams, AM McGarrigle… - Chest, 2012 - Elsevier
Objective With the increasing life expectancy for patients with cystic fibrosis (CF), and a
known predisposition to certain cancers, cumulative radiation exposure from radiologic …

[HTML][HTML] In Vitro Testing for Orally Inhaled Products: Developments in Science-Based Regulatory Approaches

B Forbes, P Bäckman, D Christopher, M Dolovich… - The AAPS journal, 2015 - Springer
This article is part of a series of reports from the “Orlando Inhalation Conference-Approaches
in International Regulation” which was held in March 2014, and coorganized by the …

[HTML][HTML] Molecular imaging of pulmonary inflammation and infection

C Giraudo, L Evangelista, AS Fraia, A Lupi… - International Journal of …, 2020 - mdpi.com
Infectious and inflammatory pulmonary diseases are a leading cause of morbidity and
mortality worldwide. Although infrequently used in this setting, molecular imaging may …

Novel outcome measures for clinical trials in cystic fibrosis

HAWM Tiddens, M Puderbach… - Pediatric …, 2015 - Wiley Online Library
Cystic fibrosis (CF) is a common inherited condition caused by mutations in the gene
encoding the CF transmembrane regulator protein. With increased understanding of the …

What can computed tomography and magnetic resonance imaging tell us about ventilation?

BA Simon, DW Kaczka, AA Bankier… - Journal of Applied …, 2012 - journals.physiology.org
This review provides a summary of pulmonary functional imaging approaches for
determining pulmonary ventilation, with a specific focus on multi-detector x-ray computed …

Cystic fibrosis: detecting changes in airway inflammation with FDG PET/CT

R Amin, M Charron, L Grinblat, A Shammas… - Radiology, 2012 - pubs.rsna.org
Purpose To determine if fluorine 18 fluorodeoxyglucose (FDG) positron emission
tomographic (PET)/computed tomographic (CT) imaging can depict a treatment effect from …

18F-fluorodeoxyglucose-PET/CT imaging of lungs in patients with cystic fibrosis

M Klein, M Cohen-Cymberknoh, S Armoni, D Shoseyov… - Chest, 2009 - Elsevier
Background Airway inflammation plays a critical role in the progression of cystic fibrosis (CF)
lung disease, and in the destruction of airways and lung parenchyma. Current methods to …

18F-Fluorodeoxyglucose Positron Emission Tomographic Imaging of Pulmonary Functions, Pathology, and Drug Delivery

MB Dolovich - Proceedings of the American Thoracic Society, 2009 - atsjournals.org
18F-FDG positron emission tomographic (PET) scanning is a major imaging tool widely
used to investigate lung function and lung disease. Tomographic imaging of drug delivered …