Among ventilated children, the incidence of acute lung injury (ALI) was 9%; of that latter
group 80% developed the acute respiratory distress syndrome (ARDS). The population …

Air leak syndrome includes pulmonary interstitial emphysema, pneumothorax,
pneumomediastinum, pneumopericardium, pneumoperitoneum, subcutaneous emphysema …

Rationale: Changes in oxygenation are often used to guide the recruitment procedure
during open lung high-frequency ventilation in preterm infants. However, data on the …

The use of volume guarantee (VG) on high-frequency oscillatory ventilation (HFOV) allows
to use fixed very low high-frequency tidal volume (VThf), maintaining adequate CO2 removal …

Rationale Lung recruitment and continuous distending pressure (CDP) titration are critical
for assuring the efficacy of high-frequency ventilation (HFOV) in preterm infants. The …

Although lifesaving, mechanical ventilation can itself be responsible for damage to lung
parenchyma. This ventilator-induced lung injury is especially observed in already injured …

Objectives: During high-frequency oscillatory ventilation, an understanding of the
relationship between lung volume and lung mechanics may help clinicians better apply …

Pediatric acute respiratory distress syndrome (PARDS) remains a significant cause of
morbidity and mortality, with mortality rates as high as 50% in children with severe PARDS …

Background High-frequency oscillatory ventilation (HFOV) is a common but unproven
management strategy in paediatric critical care. Oscillator settings have been traditionally …

Background: The mode of waveform generation and circuit characteristics differ between
high-frequency oscillators. It is unknown if this influences performance. Objectives: To …