Life-threatening infectious diseases are on their way to cause a worldwide crisis, as treating
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …

Antimicrobial peptides are an abundant and diverse group of molecules that are produced
by many tissues and cell types in a variety of invertebrate, plant and animal species. Their …

The structural parameters of fluid phase bilayers composed of phosphatidylcholines with
fully saturated, mixed, and branched fatty acid chains, at several temperatures, have been …

Antimicrobial peptides (AMPs) are multi-functional peptides whose fundamental biological
role in vivo has been proposed to be the elimination of pathogenic microorganisms …

Transmembrane pores induced by amphiphilic peptides, including melittin, are often
modeled with the barrel-stave model after the alamethicin pore. We examine this …

In the last 20 years, an increasing number of studies have been reported on membrane
active peptides. These peptides exert their biological activity by interacting with the cell …

The argument and experimental evidence are presented for a two-state model that explains
the action of both helical and β-sheet antimicrobial peptides after they bind to the plasma …

This review addresses the possible consequences of a mismatch in length between the
hydrophobic part of membrane-spanning proteins and the hydrophobic bilayer thickness for …

The condensing effect of cholesterol on phospholipid bilayers was systematically
investigated for saturated and unsaturated chains, as a function of cholesterol concentration …

Based on very extensive studies on four peptides (alamethicin, melittin, magainin and
protegrin), we propose a mechanism to explain the cooperativity exhibited by the activities of …