Surviving threats: neural circuit and computational implications of a new taxonomy of defensive behaviour
Research on defensive behaviour in mammals has in recent years focused on elicited
reactions; however, organisms also make active choices when responding to danger. We …
reactions; however, organisms also make active choices when responding to danger. We …
Neurobiology of fear and specific phobias
R Garcia - Learning & memory, 2017 - learnmem.cshlp.org
Fear, which can be expressed innately or after conditioning, is triggered when a danger or a
stimulus predicting immediate danger is perceived. Its role is to prepare the body to face this …
stimulus predicting immediate danger is perceived. Its role is to prepare the body to face this …
[HTML][HTML] A central alarm system that gates multi-sensory innate threat cues to the amygdala
Perception of threats is essential for survival. Previous findings suggest that parallel
pathways independently relay innate threat signals from different sensory modalities to …
pathways independently relay innate threat signals from different sensory modalities to …
Defensive responses: Behaviour, the brain and the body
YT Tseng, B Schaefke, P Wei, L Wang - Nature Reviews Neuroscience, 2023 - nature.com
Most animals live under constant threat from predators, and predation has been a major
selective force in shaping animal behaviour. Nevertheless, defence responses against …
selective force in shaping animal behaviour. Nevertheless, defence responses against …
Divergent midbrain circuits orchestrate escape and freezing responses to looming stimuli in mice
Animals respond to environmental threats, eg looming visual stimuli, with innate defensive
behaviors such as escape and freezing. The key neural circuits that participate in the …
behaviors such as escape and freezing. The key neural circuits that participate in the …
Cognitive control of escape behaviour
When faced with potential predators, animals instinctively decide whether there is a threat
they should escape from, and also when, how, and where to take evasive action. While …
they should escape from, and also when, how, and where to take evasive action. While …
Neural computations of threat
I Levy, D Schiller - Trends in cognitive sciences, 2021 - cell.com
A host of learning, memory, and decision-making processes form the individual's response
to threat and may be disrupted in anxiety and post-trauma psychopathology. Here we review …
to threat and may be disrupted in anxiety and post-trauma psychopathology. Here we review …
Organizing memories for generalization in complementary learning systems
Memorization and generalization are complementary cognitive processes that jointly
promote adaptive behavior. For example, animals should memorize safe routes to specific …
promote adaptive behavior. For example, animals should memorize safe routes to specific …
Inhibitory top-down projections from zona incerta mediate neocortical memory
Top-down projections convey a family of signals encoding previous experiences and current
aims to the sensory neocortex, where they converge with external bottom-up information to …
aims to the sensory neocortex, where they converge with external bottom-up information to …
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety
Fear-related disorders (for example, phobias and anxiety) cause a substantial public health
problem. To date, studies of the neural basis of fear have mostly focused on the amygdala …
problem. To date, studies of the neural basis of fear have mostly focused on the amygdala …