Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

Hallmarks of cardiovascular ageing

M Abdellatif, PP Rainer, S Sedej… - Nature Reviews …, 2023 - nature.com
Normal circulatory function is a key determinant of disease-free life expectancy (healthspan).
Indeed, pathologies affecting the cardiovascular system, which are growing in prevalence …

[HTML][HTML] Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

M1/M2 re-polarization of kaempferol biomimetic NPs in anti-inflammatory therapy of atherosclerosis

J Zhao, L Ling, W Zhu, T Ying, T Yu, M Sun… - Journal of Controlled …, 2023 - Elsevier
Atherosclerosis (AS), a leading cause of death worldwide, involves chronic macrophage
inflammation from its initiation to the emergence of complications. Targeting plaque …

Translational opportunities of single-cell biology in atherosclerosis

MPJ De Winther, M Bäck, P Evans… - European heart …, 2023 - academic.oup.com
The advent of single-cell biology opens a new chapter for understanding human biological
processes and for diagnosing, monitoring, and treating disease. This revolution now …

Effects of lifestyle factors on leukocytes in cardiovascular health and disease

H Janssen, LL Koekkoek, FK Swirski - Nature Reviews Cardiology, 2024 - nature.com
Exercise, stress, sleep and diet are four distinct but intertwined lifestyle factors that influence
the cardiovascular system. Abundant epidemiological, clinical and preclinical studies have …

Targeting endothelial vascular cell adhesion molecule-1 in atherosclerosis: drug discovery and development of vascular cell adhesion molecule-1–directed novel …

JR Pickett, Y Wu, LF Zacchi, HT Ta - Cardiovascular Research, 2023 - academic.oup.com
Vascular cell adhesion molecule-1 (VCAM-1) has been well established as a critical
contributor to atherosclerosis and consequently as an attractive therapeutic target for anti …

Atherosclerotic cardiovascular risk as an emerging priority in pediatrics

HS Schipper, S de Ferranti - Pediatrics, 2022 - publications.aap.org
Over the last decades, childhood and adolescence have emerged as an important window
of opportunity to prevent atherosclerotic cardiovascular disease (ASCVD) later in life. Here …

[HTML][HTML] Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation

MC Martinez-Campanario, M Cortés… - Nature …, 2023 - nature.com
Accumulation of lipid-laden macrophages within the arterial neointima is a critical step in
atherosclerotic plaque formation. Here, we show that reduced levels of the cellular plasticity …

[HTML][HTML] Atherosclerosis from Newborn to Adult—Epidemiology, Pathological Aspects, and Risk Factors

AC Luca, SG David, AG David, V Țarcă, IA Pădureț… - Life, 2023 - mdpi.com
Cardiovascular disease is the leading cause of mortality and morbidity throughout the world,
accounting for 16.7 million deaths each year. The underlying pathological process for the …