Protein arginine methyltransferases (PRMTs) promote the methylation of numerous proteins
at their arginine residues. An increasing number of publications have suggested that …

Atherosclerosis remains a leading cause of cardiovascular diseases. Although the
mechanism for atherosclerosis is complex and has not been fully understood, inflammation …

Atherosclerosis is a lipid-driven immune-inflammatory disease that affects the arteries,
leading to multifocal plaque development. The inflammatory process involves the activation …

Given the multifactorial pathogenesis of atherosclerosis (AS), a chronic inflammatory
disease, combination therapy arises as a compelling approach to effectively address the …

Delayed healing of traumatic wounds often stems from a dysregulated immune response
initiated or exacerbated by existing comorbidities, multiple tissue injury or wound …

Cardiovascular diseases are the leading cause of death globally, and atherosclerosis is the
major contributor to the development and progression of cardiovascular diseases. Immune …

Diabetic kidney disease (DKD) is a common complication of diabetes mellitus and a major
cause of end-stage kidney disease (ESKD). The pathogenesis of DKD is very complex and …

Objective Inflammatory bowel disease (IBD) is not only a chronic inflammatory disorder of
the gastrointestinal tract but also accompanied by systemic inflammation. The onset of …

Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic
strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA) is a major water …

Innate immune pathways play a crucial role in the development of atherosclerosis, from
sensing initial danger signals to the long-term reprogramming of immune cells. Despite the …