Familial isolated pituitary adenomas: an emerging clinical entity

F Martucci, G Trivellin, M Korbonits - Journal of endocrinological …, 2012 - Springer
Familial pituitary tumors are increasingly recognized. While some of these cases are related
to well-known syndromic conditions such as multiple endocrine neoplasia type 1 (MEN1) or …

Proteomic and functional profiles of a follicle‐stimulating hormone positive human nonfunctional pituitary adenoma

X Wang, T Guo, F Peng, Y Long, Y Mu, H Yang… - …, 2015 - Wiley Online Library
Nonfunctional pituitary adenoma (NFPA) is highly heterogeneous with different hormone‐
expressed subtypes in NFPA tissues including follicle‐stimulating hormone (FSH) positive …

[HTML][HTML] The role of aberrant DNA methylation in misregulation of gene expression in gonadotroph nonfunctioning pituitary tumors

P Kober, J Boresowicz, N Rusetska, M Maksymowicz… - Cancers, 2019 - mdpi.com
Gonadotroph nonfunctioning pituitary adenomas (NFPAs) are common intracranial tumors,
but the role of aberrant epigenetic regulation in their development remains poorly …

Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development

MV Recouvreux, EY Faraoni, MA Camilletti… - Frontiers in …, 2018 - Elsevier
Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in
tumor size, behavior and incidence have been described. These differences have been …

hTERT promoter methylation in pituitary adenomas

M Köchling, C Ewelt, G Fürtjes, S Peetz-Dienhart… - Brain tumor …, 2016 - Springer
Telomerase reverse transcriptase (TERT) expression is a hallmark in tumorigenesis and
upregulated due to mutations and methylation of the human (h) TERT promoter. As …

Reversal of endogenous dopamine receptor silencing in pituitary cells augments receptor-mediated apoptosis

H Al-Azzawi, K Yacqub-Usman, A Richardson… - …, 2011 - academic.oup.com
Dopamine (DA)-agonist targeting of the DA D2 receptor (D2R) in prolactinomas is the first-
line treatment choice for suppression of prolactin and induction of tumor shrinkage …

Proliferation markers of human pituitary tumors: contribution of a genome-wide transcriptome approach

A Wierinckx, G Raverot, N Nazaret… - Molecular and cellular …, 2010 - Elsevier
Predicting pituitary tumor behavior remains a challenge, since the prognostic value of
identified pathological markers has not yet been evaluated. Genome-wide transcriptome …

[HTML][HTML] Make way for the 'next generation': application and prospects for genome-wide, epigenome-specific technologies in endocrine research

RD Emes, WE Farrell - Journal of molecular endocrinology, 2012 - jme.bioscientifica.com
Epigenetic changes, which target DNA and associated histones, can be described as a
pivotal mechanism of interaction between genes and the environment. The field of …

[PDF][PDF] Clinicopathological classification and molecular markers of pituitary tumours for personalized therapeutic strategies

G Raverot, E Jouanneau, J Trouillas - Eur J Endocrinol, 2014 - Citeseer
Pituitary tumours, the most frequent intracranial tumour, are historically considered benign.
However, various pieces of clinical evidence and recent advances in pathological and …

[HTML][HTML] Protein western array analysis in human pituitary tumours: insights and limitations

A Ribeiro-Oliveira, G Franchi, B Kola… - Endocrine-related …, 2008 - erc.bioscientifica.com
Total thyroidectomy and central neck dissection are the procedures of choice in patients
affected with medullary thyroid cancer. It is known that a medullary thyroid cancer with node …