OBJECTIVE: The early diagnosis of nonfunctioning pituitary adenoma (NFPA) is difficult. The
objective of this study was to find specific protein biomarkers to aid in the early detection of …

Among all the hormone-secreting pituitary tumours, prolactinomas are the most frequently
found in the clinic. Since dopamine is the primary inhibitor of lactotroph function, dopamine …

Genetic cases of congenital pituitary hormone deficiency are common and many are caused
by transcription factor defects. Mouse models with orthologous mutations are invaluable for …

Prolactinomas are harmful to human health, and the clinical first‐line treatment drug is
bromocriptine. However, 20% prolactinomas patients did not respond to bromocriptine …

Although multiple different cancers have been described, it is likely that these tumour types
share a small, and common, number of newly acquired functional capabilities. Tumours that …

Acromegaly is a disorder of excessive growth hormone secretion and resultant serum
elevations in insulin-like growth factor 1. Prolonged exposure to elevated levels of these …

Prolactinomas are the most common pituitary tumors. The mechanisms of cell-cycle
regulators underlying their invasive biological behavior and poor prognosis have not yet …

This manuscript is based on an invitation lecture entitled “The Year in Pituitary” presented at
the Combined 94th Annual Meeting of The Endocrine Society and of the International …

Introduction: Pituitary adenomas are the third most common intracranial tumours. The 2004
WHO classification of pituitary adenomas has recommended the use of …

Pituitary Tumor Transforming Gene (PTTG) of human is known as a checkpoint gene in the
middle and late stages of mitosis, and is also a proto-oncogene that promotes cell cycle …