Evolution of the SARS‐CoV‐2 omicron variants BA. 1 to BA. 5: implications for immune escape and transmission
LB Shrestha, C Foster, W Rawlinson… - Reviews in Medical …, 2022 - Wiley Online Library
The first dominant SARS‐CoV‐2 Omicron variant BA. 1 harbours 35 mutations in its Spike
protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …
protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …
Omicron variant (B. 1.1. 529): infectivity, vaccine breakthrough, and antibody resistance
The latest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant Omicron
(B. 1.1. 529) has ushered panic responses around the world due to its contagious and …
(B. 1.1. 529) has ushered panic responses around the world due to its contagious and …
Efficacy and safety of the RBD-dimer–based COVID-19 vaccine ZF2001 in adults
L Dai, L Gao, L Tao, SR Hadinegoro… - New England journal …, 2022 - Mass Medical Soc
Background The ZF2001 vaccine, which contains a dimeric form of the receptor-binding
domain of severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an …
domain of severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an …
COVID-19 vaccination: The road ahead
DM Altmann, RJ Boyton - Science, 2022 - science.org
A diverse array of successful, first-generation SARS-CoV-2 vaccines have played a huge
role in efforts to bring the COVID-19 pandemic under control, even though inequitable …
role in efforts to bring the COVID-19 pandemic under control, even though inequitable …
COVID-19 vaccine development: milestones, lessons and prospects
M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
The emerging SARS-CoV-2 variants of concern (VOCs) threaten the effectiveness of current
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution
J Zahradník, S Marciano, M Shemesh, E Zoler… - Nature …, 2021 - nature.com
SARS-CoV-2 variants of interest and concern will continue to emerge for the duration of the
COVID-19 pandemic. To map mutations in the receptor-binding domain (RBD) of the spike …
COVID-19 pandemic. To map mutations in the receptor-binding domain (RBD) of the spike …
The humoral response and antibodies against SARS-CoV-2 infection
Two and a half years into the COVID-19 pandemic, we have gained many insights into the
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …