Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Inflammation is a defensive reaction for external stimuli to the human body and generally
accompanied by immune responses, which is associated with multiple diseases such as …

Reactive oxygen species (ROS) are highly reactive molecules that can oxidize proteins,
lipids, and DNA. Under physiological conditions, ROS are mainly generated in the …

Osteoporosis is widely regarded as one of the typical aging-related diseases due to the
impairment of bone remodeling. The silent information regulator of transcription1 (SIRT1) is …

Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

New strategies to block the immune evasion activity of programmed death ligand-1 (PD-L1)
are urgently needed. When exploring the PD-L1-targeted effects of mechanistically diverse …

In this review, special emphasis will be placed on red grape polyphenols for their antioxidant
and anti-inflammatory activities. Therefore, their capacity to inhibit major pathways …

Inflammation and reactive oxygen species (ROS) play important roles in the pathogenesis of
atherosclerosis. Resveratrol has been shown to possess anti-inflammatory and antioxidative …

The intestinal epithelium acts as a key defensive barrier that protects internal organs from
the detrimental gut environment. The homeostasis of the gut epithelium may be altered by …

Autoimmune diseases are still considered to be pressing concerns due the fact that they are
leaders in death and disability causes worldwide. Resveratrol is a polyphenol derived from a …