Stem cell niche: Dynamic neighbor of stem cells

A Singh, CB Yadav, N Tabassum, AK Bajpeyee… - European Journal of …, 2019 - Elsevier
Stem cell niche is a specialized and dynamic microenvironment around the stem cells which
plays a critical role in maintaining the stemness properties of stem cells. Over the years …

Induced fetal human muscle stem cells with high therapeutic potential in a mouse muscular dystrophy model

M Zhao, A Tazumi, S Takayama… - Stem cell reports, 2020 - cell.com
Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle-wasting disease
caused by DYSTROPHIN deficiency. Cell therapy using muscle stem cells (MuSCs) is a …

Influence of exercise and aging on extracellular matrix composition in the skeletal muscle stem cell niche

K Garg, MD Boppart - Journal of applied physiology, 2016 - journals.physiology.org
Skeletal muscle is endowed with a remarkable capacity for regeneration, primarily due to the
reserve pool of muscle resident satellite cells. The satellite cell is the physiologically …

Native collagen VI delays early muscle stem cell differentiation

S Metti, F Da Ros, G Toniato, M Cescon… - Journal of Cell …, 2024 - journals.biologists.com
Adult muscle stem cells (MuSCs) are critical for muscle homeostasis and regeneration, and
their behavior relies on a finely regulated niche made of specific extracellular matrix (ECM) …

Interactions between growth of muscle and stature: mechanisms involved and their nutritional sensitivity to dietary protein: the protein-stat revisited

DJ Millward - Nutrients, 2021 - mdpi.com
Childhood growth and its sensitivity to dietary protein is reviewed within a Protein-Stat model
of growth regulation. The coordination of growth of muscle and stature is a combination of …

[HTML][HTML] Characterization of hiPSC-derived muscle progenitors reveals distinctive markers for myogenic cell purification toward cell therapy

M Nalbandian, M Zhao, M Sasaki-Honda, T Jonouchi… - Stem cell reports, 2021 - cell.com
The transplantation of muscle progenitor cells (MuPCs) differentiated from human induced
pluripotent stem cells (hiPSCs) is a promising approach for treating skeletal muscle …

Collagen 18 and agrin are secreted by neural crest cells to remodel their microenvironment and regulate their migration during enteric nervous system development

N Nagy, C Barad, R Hotta, S Bhave, E Arciero… - …, 2018 - journals.biologists.com
The enteric nervous system (ENS) arises from neural crest cells that migrate, proliferate, and
differentiate into enteric neurons and glia within the intestinal wall. Many extracellular matrix …

PAX7, a key for myogenesis modulation in muscular dystrophies through multiple signaling pathways: a systematic review

NIA Rahman, CL Lam, N Sulaiman… - International Journal of …, 2023 - mdpi.com
Muscular dystrophy is a heterogenous group of hereditary muscle disorders caused by
mutations in the genes responsible for muscle development, and is generally defined by a …

[HTML][HTML] Genetic manipulation of CCN2/CTGF unveils cell-specific ECM-remodeling effects in injured skeletal muscle

JM Petrosino, A Leask, F Accornero - The FASEB Journal, 2019 - ncbi.nlm.nih.gov
In skeletal muscle, extracellular matrix (ECM) remodeling can either support the complete
regeneration of injured muscle or facilitate pathologic fibrosis and muscle degeneration …

Three-dimensional niche stiffness synergizes with Wnt7a to modulate the extent of satellite cell symmetric self-renewal divisions

LA Moyle, RY Cheng, H Liu, S Davoudi… - Molecular biology of …, 2020 - Am Soc Cell Biol
Satellite cells (SCs), the resident adult stem cells of skeletal muscle, are required for tissue
repair throughout life. While many signaling pathways are known to control SC self-renewal …