Biomarkers in progressive fibrosing interstitial lung disease: optimizing diagnosis, prognosis, and treatment response

WS Bowman, GA Echt, JM Oldham - Frontiers in Medicine, 2021 - frontiersin.org
Interstitial lung disease (ILD) comprises a heterogenous group of diffuse lung disorders that
commonly result in irreversible pulmonary fibrosis. While idiopathic pulmonary fibrosis (IPF) …

Acute exacerbations of interstitial lung diseases: Focus on biomarkers

F Drakopanagiotakis, P Markart… - International Journal of …, 2023 - mdpi.com
Interstitial lung diseases (ILDs) are a large group of pulmonary disorders characterized
histologically by the cardinal involvement of the pulmonary interstitium. The prototype of …

IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis

Y Nakanishi, Y Horimasu, K Yamaguchi, S Sakamoto… - PLoS …, 2021 - journals.plos.org
Idiopathic pulmonary fibrosis is a chronic, fibrosing interstitial pneumonia that presents with
various clinical courses and progression ranging from rapid to slow. To identify novel …

Targeting progression in pulmonary fibrosis: an overview of underlying mechanisms, molecular biomarkers, and therapeutic intervention

V D'Agnano, DF Mariniello, M Ruotolo, G Quarcio… - Life, 2024 - mdpi.com
Interstitial lung diseases comprise a heterogenous range of diffuse lung disorders,
potentially resulting in pulmonary fibrosis. While idiopathic pulmonary fibrosis has been …

Japanese clinical practice guide 2022 for hypersensitivity pneumonitis

H Tomioka, Y Miyazaki, Y Inoue, R Egashira… - Respiratory …, 2024 - Elsevier
Considering recently published two guidelines for the diagnosis of hypersensitivity
pneumonitis (HP), the Japanese Respiratory Society (JRS) has now published its own …

Asthma and post-asthmatic fibrosis: a search for new promising molecular markers of transition from acute inflammation to pulmonary fibrosis

IA Savin, AV Markov, MA Zenkova, AV Sen'kova - Biomedicines, 2022 - mdpi.com
Asthma is a heterogeneous pulmonary disorder, the progression and chronization of which
leads to airway remodeling and fibrogenesis. To understand the molecular mechanisms of …

Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid is associated with poor prognosis in idiopathic pulmonary fibrosis

K Yamaguchi, H Iwamoto, W Mazur, S Miura… - Respiratory …, 2020 - Springer
Background The endogenous secretory receptor for advanced glycation end products
(esRAGE) is a soluble isoform produced by alternative splicing of the RAGE gene. The …

Diagnosis of Fibrotic Hypersensitivity Pneumonitis: Is There a Role for Biomarkers?

JO Pereira, V Fernandes, TM Alfaro, S Freitas… - Life, 2023 - mdpi.com
Hypersensitivity pneumonitis is a complex interstitial lung syndrome and is associated with
significant morbimortality, particularly for fibrotic disease. This condition is characterized by …

Cytokines explored in saliva and tears from radiated cancer patients correlate with clinical manifestations, influencing important immunoregulatory cellular pathways

LA Aqrawi, X Chen, H Hynne, C Amdal, S Reppe… - Cells, 2020 - mdpi.com
Although radiotherapy is a common form of treatment for head and neck cancer, it may lead
to tissue damage in the salivary and lacrimal glands, possibly affecting cytokine expression …

[HTML][HTML] Metabolic landscape dysregulation in bronchoalveolar lavage fluid of checkpoint inhibitor pneumonitis

W Yu, Y He, Y Shang, T Guo, K Wang, H Liang, J Xue… - Clinical …, 2023 - Elsevier
Background Checkpoint inhibitor pneumonitis (CIP) is a potentially fatal adverse event
resulting from immunotherapy in patients with malignant tumors. However, the pathogenesis …