Cellular processes are dictated by the active signaling of proteins relaying messages to
regulate cell proliferation, apoptosis, signal transduction and cell communications. An …

Alternative polyadenylation (APA) is a gene regulatory process that dictates mRNA 3′-UTR
length, resulting in changes in mRNA stability and localization. APA is frequently disrupted …

UHMK1, a serine/threonine kinase with a U2AF homology motif, is implicated in RNA
processing and protein phosphorylation. Increasing evidence has indicated its involvement …

Telomeres are repetitive nucleotide sequences at the ends of each chromosome. It has
been hypothesized that telomere attrition evolved as a tumor suppressor mechanism in …

This study investigates the association of CD105 (endoglin) with the invasiveness of
paclitaxel-resistant ovarian cancer (OC) cells and explores the potential mechanism. A …

Research question Could METTL3 and METTL14-mediated N 6-methyladenosine (m 6 A)
modification play possible cooperative roles in pathogenesis and progression of …

Aberrant expression of forkhead box transcription factor 1 (FOXM1) plays critical roles in a
variety of human malignancies and predicts poor prognosis. However, little is known about …

As a major source of cellular serine and threonine phosphatase activity, protein
phosphatase-2A (PP2A) modulates signaling pathways in health and disease. PP2A …

Human epithelial stem cells (ESCs) are characterized by long‐term regenerative properties,
much dependent on the tissue of origin and varying during their lifespan. We analysed such …

MicroRNAs (miRNAs) have emerged as a potential class of biomolecules for diagnostic
biomarker applications. miRNAs are small non-coding RNA molecules, produced and …