Medicinal Plant Extracts Evaluated In Vitro and In Vivo for Antidiabetic Activities in Ethiopia: Bases for Future Clinical Trials and Related Investigations

BB Yikna, AS Yehualashet - Evidence‐Based Complementary …, 2021 - Wiley Online Library
Background. Diabetes mellitus (DM) is a metabolic disorder characterized by a persistent
rise in the blood glucose level resulting from defects in cellular insulin function, secretion, or …

[HTML][HTML] Pharmacological evaluation of medicinal plants with antidiabetic activities in Ethiopia: A review

ZD Kifle, M Abdelwuhab, AD Melak, T Meseret… - Metabolism open, 2022 - Elsevier
Diabetes mellitus is a serious, chronic disease that occurs either when the pancreas does
not produce enough insulin, or when the body can't effectively use insulin. Herbal medicines …

Evaluation of Anti-Diabetic and Anti-Hyperlipidemic Activities of Hydro-Alcoholic Crude Extract of the Shoot Tips of Crinum abyssinicum Hochst. ex A. Rich …

BA Tegegne, AB Mekuria, EM Birru - Journal of experimental …, 2022 - Taylor & Francis
Background Despite the availability of synthetic antihyperglycaemic medications on the
market, diabetes is on the rise. Though not scientifically proven, the Crinum abyssinicum …

Potential application of some lamiaceae species in the management of diabetes

NGER Etsassala, AA Hussein, F Nchu - Plants, 2021 - mdpi.com
Diabetes is one of the most dangerous metabolic disorders, with high rates of mortality
worldwide. Since ancient times, medicinal plants have been used in traditional medicine to …

Phytochemical bioaccessibility and in vitro antidiabetic effects of Chinese sumac (Rhus chinensis Mill.) fruits after a simulated digestion: insights into the mechanisms …

Y Fu, X Liu, Q Ma, J Yi, S Cai - International Journal of Food …, 2022 - Wiley Online Library
This work studied the effects of gastrointestinal digestion on the phytochemical
bioaccessibility and in vitro anti‐diabetic effects of different fractions from Chinese sumac …

Evaluation of Pleurotus Mushroom Effects on Histopathological Changes in Organs of Diabetic Rats

SK Dubey, SN Rai, VK Singh, AK Bajpeyee… - Disease …, 2023 - Wiley Online Library
Diabetes mellitus (DM) is a metabolic disorder that can be categorized mainly into type 1
and type 2. Diabetes type 1 is caused due to β‐cell destruction, whereas type 2 is caused by …

Protective effect of Nigella sativa seed extract and its bioactive compound thymoquinone on streptozotocin-induced diabetic rats

SS Khan, KU Zaidi - Cardiovascular & Hematological Agents in …, 2024 - ingentaconnect.com
Background: The lack of a substantial breakthrough in the treatment of diabetes, a global
issue, has led to an ongoing quest for herbs that contain bioactive elements with …

Synthesis and characterization of Pyrus communis fruit extract synthesized ZnO NPs and assessed their anti-diabetic and anti-microbial potential

K Elankathirselvan, MM Al-Ansari - Environmental Research, 2024 - Elsevier
The fruit Pyrus communis, owing to its presence of phenolics and flavonoids, was chosen for
its nanoparticle's reducing and stabilizing properties. Furthermore, the zinc metal may be …

Validation of Antidiabetic and Antihyperlipidemic Effects of 80% Methanolic Extract of the Lonchocarpus laxiflorus Leaves in Streptozotocin‐Induced Diabetic Swiss …

GT Desta, YA Ferede, WS Zewdu… - Evidence‐Based …, 2022 - Wiley Online Library
Introduction. Diabetes mellitus (DM) is a chronic endocrine disorder that requires long‐term
treatment. In Ethiopian traditional medicine practice, plants have been provided with a vital …

Insulin, but not metformin, supports wound healing process in rats with streptozotocin-induced diabetes

M Mieczkowski, B Mrozikiewicz-Rakowska… - Diabetes, Metabolic …, 2021 - Taylor & Francis
Purpose Optimal glycemic control is crucial for proper wound healing in patients with
diabetes. However, it is not clear whether other antidiabetic drugs support wound healing in …