Latent infection with Mycobacterium tuberculosis (LTBI) is defined by the presence of M.
tuberculosis-specific immunity in the absence of active tuberculosis. LTBI is detected using …

Diagnosis represents only one aspect of tuberculosis (TB) control but is perhaps one of the
most challenging. The drawbacks of current tools highlight several unmet needs in TB …

Abstract Interferon-γ (IFN-γ)-induced protein 10 (IP-10 or CXCL-10) is a chemokine involved
in trafficking immune cells to inflammatory sites. Numerous studies have reported …

Tuberculosis (TB) diagnosis still remains to be a challenge with the currently used immune
based diagnostic methods particularly Interferon Gamma Release Assay due to the …

Bovine tuberculosis remains a major economic and animal welfare concern worldwide.
Cattle vaccination is being considered as part of control strategies. This approach, used …

Current WHO recommendations for monitoring treatment response in adult pulmonary
tuberculosis (TB) are sputum smear microscopy and/or culture conversion at the end of the …

Tuberculosis is a significant health problem without an effective vaccine to combat it. A
thorough understanding of the immune response and correlates of protection is needed to …

Early diagnosis and on-time effective treatment are indispensable for Tuberculosis (TB)
control-a life threatening infectious communicable disease. The conventional techniques for …

Background The Mycobacterium tuberculosis (Mtb)-specific T-cell interferon gamma release
assays (IGRAs) are useful in detecting Mtb infection but perform poorly at distinguishing …

Plasma cytokines are biomarkers of disease extent and mycobacterial burden in pulmonary
tuberculosis (PTB). Whether chemokines can perform the same role in PTB is not known. We …