The impact of anti-tuberculous antibiotics and corticosteroids on cytokine production in QuantiFERON-TB Gold In Tube assays

V Clifford, C Zufferey, S Germano, N Ryan, D Leslie… - Tuberculosis, 2015 - Elsevier
Introduction The ability to monitor and confirm adequate treatment of latent TB infection
(LTBI) would be a major advance. The potential immunomodulatory effects of anti …

IP-10 for the Diagnosis and Treatment Monitoring of Tuberculosis in Children

A Strzelak, A Komorowska-Piotrowska, A Borowa… - Diagnostics, 2024 - mdpi.com
Purpose: To determine the utility of interferon-gamma-inducible protein 10 (IP-10) for
identifying active tuberculosis (TB) and TB infection (TBI) in children in BCG-vaccinated …

Cytokine responses to quantiferon peptides in pediatric tuberculosis: a pilot study

M Armand, V Chhor, A de Lauzanne… - Journal of Infection, 2014 - Elsevier
Objectives Detailed understanding of tuberculosis (TB) immunopathology and
cytokine/chemokine responses can ultimately lead to the development of new diagnostic …

Evaluation of the IP-10 mRNA release assay for diagnosis of TB in HIV-infected individuals

Y Tang, Y Yu, Q Wang, Z Wen, R Song, Y Li… - Frontiers in Cellular …, 2023 - frontiersin.org
HIV-infected individuals are susceptible to Mycobacterium tuberculosis (M. tb) infection and
are at high risk of developing active tuberculosis (TB). Interferon-gamma release assays …

Gene-expression profiling of calves 6 and 9 months after inoculation with Mycobacterium avium subspecies paratuberculosis

J David, HW Barkema, LL Guan, J De Buck - Veterinary research, 2014 - Springer
Early detection of Johne's disease (JD) caused by Mycobacterium avium subspecies
paratuberculosis (MAP) is essential to reduce transmission; consequently, new diagnostic …

A model based on the combination of IFN-γ, IP-10, ferritin and 25-hydroxyvitamin D for discriminating latent from active tuberculosis in children

P Comella-del-Barrio, R Abellana… - Frontiers in …, 2019 - frontiersin.org
In recent years, pediatric research on tuberculosis (TB) has focused on addressing new
biomarkers with the potential to be used as immunological non-sputum-based methods for …

Machine Learning Algorithms Evaluate Immune Response to Novel Mycobacterium tuberculosis Antigens for Diagnosis of Tuberculosis

NR Meier, TM Sutter, M Jacobsen… - Frontiers in Cellular …, 2021 - frontiersin.org
Rationale Tuberculosis diagnosis in children remains challenging. Microbiological
confirmation of tuberculosis disease is often lacking, and standard immunodiagnostic …

IP-10 and MIG are compartmentalized at the site of disease during pleural and meningeal tuberculosis and are decreased after antituberculosis treatment

Q Yang, Y Cai, W Zhao, F Wu, M Zhang… - Clinical and vaccine …, 2014 - Am Soc Microbiol
The diagnosis of active tuberculosis (TB) disease remains a challenge, especially in high-
burden settings. Cytokines and chemokines are important in the pathogenesis of TB. Here …

[HTML][HTML] Accuracy of interferon-γ-induced protein 10 for diagnosing latent tuberculosis infection: a systematic review and meta-analysis

X Qiu, Y Tang, Y Yue, Y Zeng, W Li, Y Qu… - Clinical Microbiology and …, 2019 - Elsevier
Background Effective diagnostic methods for detecting latent tuberculosis infection (LTBI)
are important for its eradication. A number of studies have evaluated the use of interferon-γ …

Exploring alternative cytokines as potential biomarkers for latent tuberculosis infection in pregnant women

AR Indrati, A Sumarpo, P Atmadja, RR Wisesa… - Plos one, 2022 - journals.plos.org
Background Interferon gamma release assays (IGRAs) are widely used to determine latent
tuberculosis infection status. However, its pregnancy-affected performance and cost …