A comparison of interferon-γ and IP-10 for the diagnosis of tuberculosis

LL Holm, MV Rose, G Kimaro, IC Bygbjerg… - …, 2014 - publications.aap.org
OBJECTIVE: Interferon-γ and IP-10 release assays are diagnostic tests for tuberculosis
infection. We have compared the accuracy of IP-10 and QuantiFERON-TB Gold In-tube [QFT …

Importance of Reciprocal Balance of T Cell Immunity in Mycobacterium abscessus Complex Lung Disease

SY Kim, WJ Koh, YH Kim, BH Jeong, HY Park, K Jeon… - PloS one, 2014 - journals.plos.org
Background Little is known about the nature of the host immune response to Mycobacterium
abscessus complex (MABC) infection. The aim of the present study was to investigate …

Experimental infection models of tuberculosis in domestic livestock

BM Buddle, HM Vordermeier… - Microbiology …, 2016 - Am Soc Microbiol
In this article we present experimental Mycobacterium bovis infection models in domestic
livestock species and how these models were applied to vaccine development, biomarker …

Diagnostic benefits of adding EspC, EspF and Rv2348-B to the QuantiFERON Gold In-tube antigen combination

R Villar-Hernández, T Blauenfeldt, E García-García… - Scientific reports, 2020 - nature.com
Interferon (IFN)-γ release assays (IGRAs) are used to diagnose latent tuberculosis (TB)
infection (LTBI). To improve the accuracy of these tests, different approaches, such as …

Predominance of Th1 immune response in pleural effusion of patients with tuberculosis among other exudative etiologies

V da Cunha Lisboa, M Ribeiro-Alves… - Journal of Clinical …, 2019 - Am Soc Microbiol
Pleural tuberculosis (PlTB), a common form of extrapulmonary TB, remains a challenge in
the diagnosis among many causes of pleural effusion. We recently reported that the …

Development of a One-Step Probe Based Molecular Assay for Rapid Immunodiagnosis of Infection with M. tuberculosis Using Dried Blood Spots

T Blauenfeldt, J Heyckendorf, S Graff Jensen, C Lange… - PloS one, 2014 - journals.plos.org
Background Antigen specific release of IP-10 is the most promising alternative marker to IFN-
γ for infection with M. tuberculosis. Compared to Interferon-γ release assays (IGRA), IP-10 is …

Screening for latent tuberculosis in anti-TNF-α candidate patients in a high tuberculosis incidence setting

N Saidenberg-Kermanac'h, L Semerano… - … of tuberculosis and …, 2012 - ingentaconnect.com
BACKGROUND: Screening for latent tuberculosis infection (LTBI) using a protocol
comprising chest X-ray and tuberculin skin test (TST) interpreted with medical history, Sc1 …

Gene expression profiling and putative biomarkers of calves 3 months after infection with Mycobacterium avium subspecies paratuberculosis

J David, HW Barkema, R Mortier, S Ghosh… - Veterinary immunology …, 2014 - Elsevier
Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease (JD), a
chronic granulomatous intestinal inflammation of ruminants. Current diagnostic tools lack …

CXCR3 ligands in pleural fluid as markers for the diagnosis of tuberculous pleural effusion

W Chung, Y Jung, K Lee, J Park… - … of Tuberculosis and …, 2017 - ingentaconnect.com
SETTING: A tertiary care academic medical centre. OBJECTIVE: To evaluate the clinical
usefulness of CXC motif chemokine receptor 3 (CXCR3) ligands in tuberculous pleural …

Human B cells produce chemokine CXCL10 in the presence of Mycobacterium tuberculosis specific T cells

ST Hoff, AM Salman, M Ruhwald, P Ravn, I Brock… - Tuberculosis, 2015 - Elsevier
Background The role of B cells in human host response to Mycobacterium tuberculosis (Mtb)
infection is still controversial, but recent evidence suggest that B cell follicle like structures …