Diagnostic Performance of a Novel CXCL10 mRNA Release Assay for Mycobacterium tuberculosis Infection

L Pan, M Huang, H Jia, G Deng, Y Chen… - Frontiers in …, 2022 - frontiersin.org
One-fourth of the world's population has been infected with Mycobacterium tuberculosis (M.
tb). Although interferon-gamma release assays (IGRAs) have been shown to be valid …

Granzyme A as a potential biomarker of Mycobacterium tuberculosis infection and disease

G Guggino, V Orlando, S Cutrera, MP La Manna… - Immunology letters, 2015 - Elsevier
Cytotoxic molecules such as granulysin, perforin and granzymes produced by cytolytic T
cells directly contribute to immune defense against tuberculosis (TB). In search for novel TB …

Multiple cytokine analysis based on QuantiFERON-TB gold plus in different tuberculosis infection status: an exploratory study

L Zhang, Z Yang, F Wu, Q Ge, Y Zhang, D Li… - BMC Infectious …, 2024 - Springer
Background More efficient and convenient diagnostic method is a desperate need to reduce
the burden of tuberculosis (TB). This study explores the multiple cytokines secretion based …

Added value of IP-10 as a read-out of Mycobacterium tuberculosis: specific immunity in young children

S Jenum, S Dhanasekaran, C Ritz… - The Pediatric …, 2016 - journals.lww.com
We have explored the added value of interferon-γ (IFNγ)–inducible protein 10 as a read-out
of Mycobacterium tuberculosis–specific immunity in young Indian children, where the …

[HTML][HTML] Alternative biomarkers for classification of latent tuberculosis infection status in pregnant women with borderline Quantiferon plus results

F Tesfaye, E Sturegård, J Walles, N Winqvist… - Tuberculosis, 2020 - Elsevier
Borderline interferon-gamma (IFN-γ) results (near the cut-off level 0.35 IU/ml) occur in
QuantiFERON (QFT) assays. We investigated the performance of alternative biomarkers for …

Early cytokine and antibody responses against Coxiella burnetii in aerosol infection of BALB/c mice

T Schoffelen, JS Self, KA Fitzpatrick, MG Netea… - … and infectious disease, 2015 - Elsevier
Coxiella burnetii, a Gram-negative intracellular bacterium, can give rise to Q fever in humans
and is transmitted mainly by inhalation of infected aerosols from animal reservoirs. Serology …

IP-10 dried blood spots assay monitoring treatment efficacy in extrapulmonary tuberculosis in a low-resource setting

IM Hoel, MD Jørstad, M Marijani, M Ruhwald… - Scientific reports, 2019 - nature.com
Abstract Treatment efficacy is difficult to evaluate in extrapulmonary tuberculosis (EPTB)
patients. Interferon-γ inducible protein (IP-) 10 has been suggested as a biomarker for …

Comparable cytokine release ex-vivo by whole blood from COVID-19 patients with and without non-invasive ventilation

M Bonacini, I Ferrigno, A Rossi, N Facciolongo… - Immunobiology, 2023 - Elsevier
T cells are key players in the resolution of the infection by SARS-CoV-2. A delay in their
activation can lead to severe COVID-19. The present work aimed to identify differences in …

Expression of immune regulatory factors, chemokines and growth factors in differentiated gastric cancer cells treated with an anticancer bioactive peptide combined …

X Li, J Peng, X Su - Molecular and Clinical Oncology, 2024 - spandidos-publications.com
Gastric cancer is one of the most common malignant tumors of the digestive system. An
anticancer bioactive peptide (ACBP) was previously shown to have an important role in …

Serum IP-10 in the diagnosis of latent and active tuberculosis

V Clifford, M Tebruegge, C Zufferey… - The Journal of …, 2015 - pubmed.ncbi.nlm.nih.gov
Serum IP-10 in the diagnosis of latent and active tuberculosis Serum IP-10 in the diagnosis of
latent and active tuberculosis J Infect. 2015 Dec;71(6):696-8. doi: 10.1016/j.jinf.2015.08.001 …