Liquid biopsy in lung cancer: biomarkers for the management of recurrence and metastasis

VGP Souza, A Forder, LJ Brockley… - International Journal of …, 2023 - mdpi.com
Liquid biopsies have emerged as a promising tool for the detection of metastases as well as
local and regional recurrence in lung cancer. Liquid biopsy tests involve analyzing a …

Fundamentals and applications of metal nanoparticle-enhanced singlet oxygen generation for improved cancer photodynamic therapy

BP George, A Chota, P Sarbadhikary… - Frontiers in …, 2022 - frontiersin.org
The introduction of nanotechnology in the field of Photodynamic Therapy (PDT) has proven
to have great potential to overcome some of the challenges associated with traditional …

The roles of secreted Wnt ligands in cancer

J Werner, KE Boonekamp, T Zhan… - International Journal of …, 2023 - mdpi.com
Wnt ligands are secreted signaling proteins that display a wide range of biological effects.
They play key roles in stimulating Wnt signaling pathways to facilitate processes such as …

Epigenetic basis and targeting of cancer metastasis

R Banerjee, J Smith, MR Eccles, RJ Weeks… - Trends in Cancer, 2022 - cell.com
Despite the development of novel therapeutic approaches and improved clinical
management, survival from metastatic disease remains poor. Indeed, metastasis accounts …

The function of N-myc downstream-regulated gene 2 (NDRG2) as a negative regulator in tumor cell metastasis

KW Lee, S Lim, KD Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
N-myc downstream-regulated gene 2 (NDRG2) is a tumor-suppressor gene that suppresses
tumorigenesis and metastasis of tumors and increases sensitivity to anti-cancer drugs. In this …

[HTML][HTML] Physical activity prevents tumor metastasis through modulation of immune function

A Zheng, X Ma - Frontiers in Pharmacology, 2022 - frontiersin.org
Metastasis is responsible for 90% of deaths in cancer patients. Most patients diagnosed with
metastatic cancer will die within 5 years. PA is good for health and has become an emerging …

NK and cells with NK-like activities in cancer immunotherapy-clinical perspectives

K Mortezaee, J Majidpoor - Medical Oncology, 2022 - Springer
Natural killer (NK) cells are lymphoid cells of innate immunity that take important roles in
immune surveillance. NK cells are considered as a bridge between innate and adaptive …

miR-138-5p-mediated HOXD11 promotes cell invasion and metastasis by activating the FN1/MMP2/MMP9 pathway and predicts poor prognosis in penile squamous …

X Tan, Z Liu, Y Wang, Z Wu, Y Zou, S Luo, Y Tang… - Cell Death & …, 2022 - nature.com
The presence and extent of regional lymph node and distant metastasis are the most fatal
prognostic factors in penile squamous cell carcinoma (PSCC). However, the available …

Extracellular vesicle-based checkpoint regulation and immune state in cancer

K Mortezaee, J Majidpoor - Medical Oncology, 2022 - Springer
Tumor cells exploit several mechanisms for hijacking an immunosuppressive tumor
ecosystem in order to evade immune surveillance and to progress toward metastasis …

Dual effects of radiotherapy on tumor microenvironment and its contribution towards the development of resistance to immunotherapy in gastrointestinal and thoracic …

D Zhao, Y Mo, ME Neganova… - Frontiers in Cell and …, 2023 - frontiersin.org
Successful clinical methods for tumor elimination include a combination of surgical
resection, radiotherapy, and chemotherapy. Radiotherapy is one of the crucial components …