Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

Oocyte in vitro maturation (IVM) is an assisted reproductive technology with a long and
sometimes checked history. It is a minimally invasive technique involving the deliberate …

BACKGROUND While oocyte IVM is practiced sporadically it has not achieved widespread
clinical practice globally. However, recently there have been some seminal advances in our …

The overall oocyte quality declines with aging, and this effect is strongly associated with a
higher reactive oxygen species (ROS) level and the resultant oxidative damage. C-type …

The biggest cell in the human body, the oocyte, encloses almost the complete machinery to
start life. Despite all the research performed to date, defining oocyte quality is still a major …

Abstract Background Cattle (Bos taurus) are a major large livestock, however, compared
with other species, the transcriptional specificity of bovine oocyte development has not been …

Introduction To investigate whether rescue in vitro maturation (R-IVM) improves the
reproductive outcomes among women undergoing intracytoplasmic sperm injection (ICSI) …

Purpose In vitro maturation (IVM) is a technology that generates mature oocytes following
culture of immature cumulus-oocyte complexes (COC) in vitro. IVM is characterized by …

In vitro follicle development (IVFD) is an adequate model to obtain basic knowledge of
folliculogenesis and provides a tool for ovarian toxicity screening. IVFD yielding competent …

Research question: More than 100 variants have been identified in the TUBB8 gene, which
account for approximately 30% of infertile women with oocyte maturation defects. But what is …