An Overview of Cannabidiol as a Multifunctional Drug: Pharmacokinetics and Cellular Effects

N Martinez Naya, J Kelly, G Corna, M Golino… - Molecules, 2024 - mdpi.com
Cannabidiol (CBD), a non-psychoactive compound derived from Cannabis Sativa, has
garnered increasing attention for its diverse therapeutic potential. This comprehensive …

Cannabidiol and neurodegeneration: From molecular mechanisms to clinical benefits

SK Jha, VK Nelson, PR Suryadevara, SP Panda… - Ageing Research …, 2024 - Elsevier
Neurodegenerative disorders (NDs) such as Alzheimer's disease, Parkinson's disease,
Huntington's disease, multiple sclerosis, and amyotrophic lateral sclerosis are severe and …

Cannabidiol in sports: insights on how CBD could improve performance and recovery

D Rojas-Valverde, A Fallas-Campos - Frontiers in pharmacology, 2023 - frontiersin.org
Cannabidiol is popularly known as CBD, a substance that is part of the cannabinoids,
chemical components extracted from the cannabis or hemp plant. Of all the chemical …

The Antioxidant and Neuroprotective Potential of Leaves and Inflorescences Extracts of Selected Hemp Varieties Obtained with scCO2

A Stasiłowicz-Krzemień, S Sip, P Szulc, J Walkowiak… - Antioxidants, 2023 - mdpi.com
Cannabis sativa, a versatile plant with numerous varieties, holds promising potential for a
wide range of biological activity. As raw materials for research, we chose leaves and …

[HTML][HTML] Putative role of immune reactions in the mechanism of tardive dyskinesia

AJM Loonen - Brain, Behavior, & Immunity-Health, 2023 - Elsevier
The term extrapyramidal disorders is most often used for conditions such as Parkinson's
disease or Huntington's disease, but also refers to a group of extrapyramidal side effects of …

Anxiety Modulation by Cannabinoids—The Role of Stress Responses and Coping

J Haller - International Journal of Molecular Sciences, 2023 - mdpi.com
Endocannabinoids were implicated in a variety of pathological conditions including anxiety
and are considered promising new targets for anxiolytic drug development. The optimism …

The NLRP3 inflammasome: A vital player in inflammation and mediating the anti-inflammatory effect of CBD

F Chu, X Wang, B Li, L Xu, B Di - Inflammation Research, 2024 - Springer
Background The NLRP3 inflammasome is a vital player in the emergence of inflammation.
The priming and activation of the NLRP3 inflammasome is a major trigger for inflammation …

Cannabidiol exerts multitarget immunomodulatory effects on PBMCs from individuals with psoriasis vulgaris

C Pagano, E Ciaglia, L Coppola, V Lopardo… - Frontiers in …, 2024 - frontiersin.org
Introduction The involvement of endocannabinoid system (ECS) in the inflammatory
cascade, and the ability of phytocannabinoids, endocannabinoids and their synthetic …

Cumulative Deleterious Effects of Tetrahydrocannabinoid (THC) and Ethanol on Mitochondrial Respiration and Reactive Oxygen Species Production Are Enhanced in …

AL Charles, A Charloux, T Vogel, JS Raul… - International Journal of …, 2024 - mdpi.com
Delta 9 tetrahydrocannabinol (THC), the main component of cannabis, has adverse effects
on the cardiovascular system, but whether concomitant ethanol (EtOH) and aging modulate …

Therapeutic potential of cannabidiol (CBD) in the treatment of cardiovascular diseases

NM Naya, J Kelly, A Hogwood, A Abbate… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Cannabidiol (CBD) is the primary non-psychoactive chemical derived from
Cannabis Sativa, and its growing popularity is due to its potential therapeutic properties …