Background Post-traumatic stress disorder (PTSD) and major depressive disorder (MDD)
are psychiatric disorders that can present with overlapping symptoms and shared risk …

Background Neuropsychiatric disorders are highly heritable and have overlapping genetic
underpinnings. Single nucleotide polymorphisms (SNPs) in the gene CACNA1C have been …

Abstract Background CACNA1C rs1006737 A allele, identified as a genetic risk variant for
bipolar disorder (BD), is associated with anomalous functional connectivity in adults with …

BackgroundRecent genetic evidence implicates glutamatergic-receptor variations in
schizophrenia. Glutamatergic excess during early life in people with schizophrenia may …

Background Clinical features and genetics overlap in schizophrenia (SCZ) and bipolar
disorder (BD). Identifying brain alterations associated with genetic vulnerability for SCZ and …

Altered gene expressions may mechanistically link genetic factors with brain morphometric
alterations. Existing gene expression studies have examined selected morphometric …

Neuropsychiatric disorders are highly complex conditions and the risk of developing a
disorder has been tied to hundreds of genomic variants that alter the expression and/or …

Objective To investigate the relationship between L-type calcium channel α1C subunit
(CACNA1C) gene polymorphism and schizophrenia (SCZ) and cognitive function in the Han …

Cortical and subcortical structural alteration has been extensively reported in schizophrenia,
including the unusual expansion of gray matter volumes (GMVs) of basal ganglia (BG) …

Objectives Numerous genome-wide association studies have identified CACNA1C as one of
the top risk genes for schizophrenia. As a necessary post-genome-wide association study …