Carbapenem-resistant Pseudomonas aeruginosa (CR-PA) is a major healthcare-associated
pathogen worldwide. In the United States, 10–30% of P. aeruginosa isolates are …

The spread of carbapenemase producers in Enterobacteriaceae has now been identified
worldwide. Three main carbapenemases have been reported; they belong to three classes …

Objectives In 2017, the World Health Organization (WHO) published a list of global priority
pathogens (GPP)–12 species of bacteria with critical, high, and medium antibiotic resistance …

Antibiotic resistance in Gram-negative uropathogens is a major global concern. Worldwide,
the prevalence of Enterobacteriaceae that produce extended-spectrum β-lactamase or …

The emergence of one of the most recently described carbapenemases, namely, the New
Delhi metallo-lactamase (NDM-1), constitutes a critical and growingly important medical …

The lack of new antibiotic classes calls for a cautious use of existing agents. Yet, every 10
min, almost two tons of antibiotics are used around the world, all too often without any …

Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the
1990s, but are today encountered routinely in hospitals and other healthcare facilities in …

Over the last decades, there has been a dramatic global increase in multidrug-resistant
(MDR) pathogens particularly among Gram-negative bacteria (GNB). Pseudomonas …

The cephalosporin-β-lactamase-inhibitor-combinations, ceftolozane/tazobactam and
ceftazidime/avibactam, have revolutionized treatment of carbapenem-resistant …

The molecular epidemiology and mechanisms of resistance of carbapenem-resistant
Enterobacteriaceae (CRE) were determined in hospitals in the countries of the Gulf …