[HTML][HTML] Non-alcoholic fatty liver disease: Definition and subtypes

SK Han, SK Baik, MY Kim - Clinical and molecular hepatology, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide, with a global prevalence of approximately 30%. However, the prevalence of …

Dietary polyphenols and non-alcoholic fatty liver disease

L Abenavoli, T Larussa, A Corea, AC Procopio… - Nutrients, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), which is emerging as a major public health issue
worldwide, is characterized by a wide spectrum of liver disorders, ranging from simple fat …

Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial

AJ Sanyal, P Lopez, EJ Lawitz, KJ Lucas, J Loeffler… - Nature Medicine, 2023 - nature.com
The multimodal activities of farnesoid X receptor (FXR) agonists make this class an attractive
option to treat nonalcoholic steatohepatitis. The safety and efficacy of tropifexor, an FXR …

Head-to-head comparison between MEFIB, MAST, and FAST for detecting stage 2 fibrosis or higher among patients with NAFLD

BK Kim, N Tamaki, K Imajo, M Yoneda, N Sutter… - Journal of …, 2022 - Elsevier
Background & Aims Patients with non-alcoholic fatty liver disease (NAFLD) and significant
fibrosis (fibrosis stage≥ 2) are candidates for pharmacological trials. The aim of this study …

[HTML][HTML] Digital pathology with artificial intelligence analyses provides greater insights into treatment-induced fibrosis regression in NASH

NV Naoumov, D Brees, J Loeffler, E Chng, Y Ren… - Journal of …, 2022 - Elsevier
Background & Aims Liver fibrosis is a key prognostic determinant for clinical outcomes in
non-alcoholic steatohepatitis (NASH). Current scoring systems have limitations, especially in …

[HTML][HTML] Noninvasive imaging biomarkers for liver fibrosis in nonalcoholic fatty liver disease: current and future

JH Yu, HA Lee, SU Kim - Clinical and molecular hepatology, 2023 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent worldwide and becoming
a major cause of liver disease-related morbidity and mortality. The presence of liver fibrosis …

NAFLD, MAFLD and obesity: brothers in arms?

MV Machado, H Cortez-Pinto - Nature Reviews Gastroenterology & …, 2023 - nature.com
2022 was a proficuous year in both the nonalcoholic fatty liver disease (NAFLD) and obesity
fields. Pharmacological treatment for obesity and NAFLD is moving forward, with the …

[HTML][HTML] Noninvasive serum biomarkers for liver fibrosis in NAFLD: current and future

T Reinson, RM Buchanan, CD Byrne - Clinical and molecular …, 2023 - ncbi.nlm.nih.gov
In the last 20 years, noninvasive serum biomarkers to identify liver fibrosis in patients with
non-alcoholic fatty liver disease (NAFLD) have been developed, validated against liver …

The triglyceride glucose-body mass index: a non-invasive index that identifies non-alcoholic fatty liver disease in the general Japanese population

H Hu, Y Han, C Cao, Y He - Journal of Translational Medicine, 2022 - Springer
Background By identifying individuals at high risk for non-alcoholic fatty liver disease
(NAFLD), interventional programs could be targeted more effectively. Some studies have …

[HTML][HTML] Screening strategy for non-alcoholic fatty liver disease

S Zhang, LY Mak, MF Yuen, WK Seto - Clinical and molecular …, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease,
affecting approximately 25% of the general population worldwide, and is forecasted to …