Non-oncogene dependencies: Novel opportunities for cancer therapy

T Di Marco, M Mazzoni, A Greco, G Cassinelli - Biochemical Pharmacology, 2024 - Elsevier
Targeting oncogene addictions have changed the history of subsets of malignancies and
continues to represent an excellent therapeutic opportunity. Nonetheless, alternative …

[HTML][HTML] Pan-cancer analysis of polo-like kinase family genes reveals polo-like kinase 1 as a novel oncogene in kidney renal papillary cell carcinoma

G Zhao, Y Wang, J Zhou, P Ma, S Wang, N Li - Heliyon, 2024 - cell.com
Abstract Background Polo-like kinases (PLKs) are a kinase class of serine/threonine with
five members that play crucial roles in cell cycle regulation. However, their biological …