Unveiling cytokine charge disparity as a potential mechanism for immune regulation
JM Messina, M Luo, MS Hossan, HA Gadelrab… - Cytokine & Growth …, 2023 - Elsevier
Cytokines are small signaling proteins that regulate the immune responses to infection and
tissue damage. Surface charges of cytokines determine their in vivo fate in immune …
tissue damage. Surface charges of cytokines determine their in vivo fate in immune …
Histone lactylation bridges metabolic reprogramming and epigenetic rewiring in driving carcinogenesis: Oncometabolite fuels oncogenic transcription
Y Zhang, H Song, M Li, P Lu - Clinical and Translational …, 2024 - Wiley Online Library
Heightened lactate production in cancer cells has been linked to various cellular
mechanisms such as angiogenesis, hypoxia, macrophage polarisation and T‐cell …
mechanisms such as angiogenesis, hypoxia, macrophage polarisation and T‐cell …
HOXA9 versus HOXB9; particular focus on their controversial role in tumor pathogenesis
The Homeobox (HOX) gene family is essential to regulating cellular processes because it
maintains the exact coordination required for tissue homeostasis, cellular differentiation, and …
maintains the exact coordination required for tissue homeostasis, cellular differentiation, and …
Hypoxia-inducible factor in breast cancer: role and target for breast cancer treatment
S Zhi, C Chen, H Huang, Z Zhang, F Zeng… - Frontiers in …, 2024 - frontiersin.org
Globally, breast cancer stands as the most prevalent form of cancer among women. The
tumor microenvironment of breast cancer often exhibits hypoxia. Hypoxia-inducible factor 1 …
tumor microenvironment of breast cancer often exhibits hypoxia. Hypoxia-inducible factor 1 …
[HTML][HTML] ENO2 promotes anoikis resistance in anaplastic thyroid cancer by maintaining redox homeostasis
Y Zhang, X Ji, Y Wang - Gland Surgery, 2024 - ncbi.nlm.nih.gov
Background Anoikis presents a significant barrier in the metastasis of cancer. As the most
aggressive type of thyroid cancer, anaplastic thyroid cancer (ATC) exhibits a high risk of …
aggressive type of thyroid cancer, anaplastic thyroid cancer (ATC) exhibits a high risk of …
Parecoxib inhibits tumorigenesis and angiogenesis in hepatocellular carcinoma through ERK–VEGF/MMPs signaling pathway
L Tian, YQ Huang, Y Liu, JW Liu, Y Liu - IUBMB life - Wiley Online Library
Parecoxib, a well‐recognized nonsteroidal anti‐inflammatory drug, has been reported to
possess anticancer properties in various tumor types. In this work, we aimed to investigate …
possess anticancer properties in various tumor types. In this work, we aimed to investigate …
Lysine lactylation in the regulation of tumor biology
Z Yang, Y Zheng, Q Gao - Trends in Endocrinology & Metabolism, 2024 - cell.com
Lysine lactylation (Kla), a newly discovered post-translational modification (PTM) of lysine
residues, is progressively revealing its crucial role in tumor biology. A growing body of …
residues, is progressively revealing its crucial role in tumor biology. A growing body of …