[HTML][HTML] Effects of mechanical ventilation on the interstitial extracellular matrix in healthy lungs and lungs affected by acute respiratory distress syndrome: a narrative …

L Al-Husinat, S Azzam, S Al Sharie, AH Al Sharie… - Critical Care, 2024 - Springer
Background Mechanical ventilation, a lifesaving intervention in critical care, can lead to
damage in the extracellular matrix (ECM), triggering inflammation and ventilator-induced …

Liquid biopsy for the management of NSCLC patients under osimertinib treatment

A Ntzifa, T Marras, V Georgoulias… - Critical Reviews in …, 2024 - Taylor & Francis
Therapeutic management of NSCLC patients is quite challenging as they are mainly
diagnosed at a late stage of disease, and they present a high heterogeneous molecular …

[HTML][HTML] Fertility and reproductive concerns related to the new generation of cancer drugs and the clinical implication for young individuals undergoing treatments for …

H Helgadottir, A Matikas, J Fernebro, JE Frödin… - European Journal of …, 2024 - Elsevier
The treatment landscape of solid tumors has changed markedly in the last years.
Molecularly targeted treatments and immunotherapies have been implemented and have, in …

Integrated whole‐exome and bulk transcriptome sequencing delineates the dynamic evolution from preneoplasia to invasive lung adenocarcinoma featured with …

D Zhou, Y Li, Q Liu, X Deng, L Chen, M Li… - Cancer …, 2024 - Wiley Online Library
Objective The genomic and molecular ecology involved in the stepwise continuum
progression of lung adenocarcinoma (LUAD) from adenocarcinoma in situ (AIS) to minimally …

[HTML][HTML] Imaging at the nexus: how state of the art imaging techniques can enhance our understanding of cancer and fibrosis

A Baniasadi, JP Das, CM Prendergast… - Journal of …, 2024 - ncbi.nlm.nih.gov
Both cancer and fibrosis are diseases involving dysregulation of cell signaling pathways
resulting in an altered cellular microenvironment which ultimately leads to progression of the …

Real-World Treatment Patterns and Survival Outcomes for Patients with Non-Metastatic Non-Small-Cell Lung Cancer in Sweden: A Nationwide Registry Analysis from …

GN Oskarsdottir, E Lampa, A Berglund, L Rosengren… - Cancers, 2024 - mdpi.com
Simple Summary Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-
related death worldwide, with almost half of all patients diagnosed with non-metastatic …

[HTML][HTML] Transcriptome Analysis of the Inhibitory Effects of 20 (S)-Protopanaxadiol on NCI-H1299 Non-Small Cell Lung Cancer Cells

Z Cong, X Zhang, Z Lv, J Jiang, L Wang, J Li, J Wang… - Molecules, 2023 - mdpi.com
Lung cancer seriously threatens human health. To explore the molecular mechanism of 20
(S)-Protopanaxadiol (PPD) on human non-small cell lung cancer cells, we investigated the …

[HTML][HTML] Healthcare Resource Utilization and Associated Costs among Patients with Advanced Non-Small-Cell Lung Cancer Receiving Chemotherapy or …

J Ginés Rubió, O Delgado, A Callejo, M Domínguez… - Cancers, 2024 - mdpi.com
Simple Summary This observational, single-center, retrospective study aimed to describe
the real-world (RW) healthcare resource utilization (HCRU) among patients with advanced …

Microsatellite Instability, Mismatch Repair, and Tumor Mutation Burden in Lung Cancer

OC Rosca, OE Vele - Surgical Pathology Clinics, 2024 - surgpath.theclinics.com
Microsatellite Instability, Mismatch Repair, and Tumor Mutation Burden in Lung Cancer -
Surgical Pathology Clinics Skip to Main Content Skip to Main Menu Advertisement Surgical …

Genome-Wide Analysis Identifies Nuclear Factor 1C as a Novel Transcription Factor and Potential Therapeutic Target in SCLC

V Shukla, H Wang, L Varticovski, S Baek… - Journal of Thoracic …, 2024 - Elsevier
Introduction Recent insights regarding mechanisms mediating stemness, heterogeneity, and
metastatic potential of lung cancers have yet to be fully translated to effective regimens for …