[HTML][HTML] The role of matrix metalloproteinase 9 in fibrosis diseases and its molecular mechanisms

Y Wang, L Jiao, C Qiang, C Chen, Z Shen… - Biomedicine & …, 2024 - Elsevier
Fibrosis is a process of tissue repair that results in the slow creation of scar tissue to replace
healthy tissue and can affect any tissue or organ. Its primary feature is the massive …

The role of N6-methyladenosine (m6A) in kidney diseases

L You, Z Han, H Chen, L Chen, Y Lin, B Wang… - Frontiers in …, 2023 - frontiersin.org
Chemical modifications are a specific and efficient way to regulate the function of biological
macromolecules. Among them, RNA molecules exhibit a variety of modifications that play …

Physical exercise as a friend not a foe in acute kidney diseases through immune system modulation

AC Costanti-Nascimento, L Brelaz-Abreu… - Frontiers in …, 2023 - frontiersin.org
Regular and moderate exercise is being used for therapeutic purposes in treating several
diseases, including cancer, cardiovascular diseases, arthritis, and even chronic kidney …

Farnesol Inhibits PI3 Kinase Signaling and Inflammatory Gene Expression in Primary Human Renal Epithelial Cells

A Müller, M Lozoya, X Chen, V Weissig, M Nourbakhsh - Biomedicines, 2023 - mdpi.com
Chronic inflammation and elevated cytokine levels are closely associated with the
progression of chronic kidney disease (CKD), which is responsible for the manifestation of …

Role of mitochondria in pathogenesis and therapy of renal fibrosis

X Zhao, Y Li, J Yu, H Teng, S Wu, Y Wang, H Zhou, F Li - Metabolism, 2024 - Elsevier
Renal fibrosis, specifically tubulointerstitial fibrosis, represents the predominant pathological
consequence observed in the context of progressive chronic kidney conditions. The …

The role of non-protein-coding RNAs in ischemic acute kidney injury

F Sabet Sarvestani, A Afshari, N Azarpira - Frontiers in Immunology, 2024 - frontiersin.org
Acute kidney injury (AKI) is a condition characterized by a rapid decline in kidney function
within a span of 48 hours. It is influenced by various factors including inflammation, oxidative …

[HTML][HTML] Emerging Insights Into Necroptosis: Implications for Renal Health and Diseases

A Gupta, S Chakole, S Agrawal, H Khekade, R Prasad… - Cureus, 2023 - ncbi.nlm.nih.gov
Necroptosis is a regulated form of cell death that has gained increasing attention in recent
years. It plays a significant role in various physiological and pathological processes …

The Role of the Complement System in the Pathogenesis of Infectious Forms of Hemolytic Uremic Syndrome

PP Avdonin, MS Blinova, GA Generalova, KM Emirova… - Biomolecules, 2023 - mdpi.com
Hemolytic uremic syndrome (HUS) is an acute disease and the most common cause of
childhood acute renal failure. HUS is characterized by a triad of symptoms: microangiopathic …

Immunosenescence and Immune Exhaustion Are Associated with Levels of Protein-Bound Uremic Toxins in Patients on Hemodialysis

T Tourountzis, G Lioulios, S Van Laecke… - Biomedicines, 2023 - mdpi.com
Background: The accumulation of protein-bound uremic toxins (PBUTs) in chronic kidney
disease may affect patients' immune status. The aim of the study was to evaluate their …

Glucocorticoid does not improve the renal prognosis of patients with diabetic nephropathy combined with acute tubulointerstitial nephritis: a retrospective analysis

J Tian, J Shi, Y Jiao, X Liu, J An, Y Yang, G Zou… - Renal …, 2024 - Taylor & Francis
Background and objectives In clinical practice, some patients are diagnosed with diabetic
nephropathy (DN) combined with acute tubulointerstitial nephritis (ATIN) through renal …