Two Sides of The Same Coin: Normal and Tumoral Stem Cells, The Relevance of In Vitro Models and Therapeutic Approaches: The Experience with Zika Virus in …

R Tinnirello, CM Chinnici, V Miceli, R Busà… - International Journal of …, 2023 - mdpi.com
Neural stem cells (NSCs) were described for the first time more than two decades ago for
their ability to differentiate into all neural cell lineages. The isolation of NSCs from adults and …

Multiple functions of Hes genes in the proliferation and differentiation of neural stem cells

N Hu, L Zou - Annals of Anatomy-Anatomischer Anzeiger, 2022 - Elsevier
The HES proteins (hairy and Enhancer of split (E (spl)) homologs) are basic helix-loop-helix
(bHLH) transcription factors that regulate the proliferation and differentiation of stem cells …

microRNA‐9‐5p alleviates blood–brain barrier damage and neuroinflammation after traumatic brain injury

J Wu, J He, X Tian, Y Luo, J Zhong… - Journal of …, 2020 - Wiley Online Library
Abstract The level of microRNA‐9‐5p (miRNA‐9‐5p) in brain tissues is significantly changed
after traumatic brain injury (TBI). However, the effect of miRNA‐9‐5p for brain function in TBI …

Upregulation of miRNA-9-5p promotes angiogenesis after traumatic brain injury by inhibiting Ptch-1

J Wu, J He, X Tian, H Li, Y Wen, Q Shao, C Cheng… - Neuroscience, 2020 - Elsevier
Abstract MicroRNA-9-5p (miRNA-9-5p) is an important regulator of angiogenesis in many
pathological states. However, the effect of miRNA-9-5p on angiogenesis after traumatic …

First passage time properties of miRNA-mediated protein translation

K Biswas, MK Jolly, A Ghosh - Journal of Theoretical Biology, 2021 - Elsevier
An important function of microRNAs in gene regulation is to repress the protein synthesis in
a multi-step process with implications in timing efficiency of the regulatory network. We …

Deciphering the impact of pulsatile input in the population-level synchrony of the Hes1 oscillators

A Giri, S Kar - Journal of Chemical Sciences, 2023 - Springer
Cell-to-cell communication via different signalling pathways often results in population-level
synchronization of certain gene expressions in noisy cellular environments organized. How …

Deciphering the Role of Fluctuation Dependent Intercellular Communication in Neural Stem Cell Development

A Giri, D Sengupta, S Kar - ACS Chemical Neuroscience, 2021 - ACS Publications
Neural stem cells (NPCs) efficiently communicate in an intercellular manner to govern
specific cell fate decisions during the developmental process despite withstanding the …

Stability and bifurcation analysis of a diffusive miR-9/Hes1 network with time delay

C Li, H Liu, T Zhang, Y Zhang - IEEE/ACM Transactions on …, 2021 - ieeexplore.ieee.org
In this paper, a model of miR-9/Hes1 interaction network involving one time delay and
diffusion effect under the Neumann boundary conditions is studied. First of all, the stability of …